Gramotina L I
Antibiotiki. 1977 Aug;22(8):704-8.
Capacity for production of bactericin was found in the spheroplasts of the strains of the rodent pseudotuberculosis microbe. The author named it as pseudotuberculocin. The bacteriocin production was not detected in the initial strains of the pseudotuberculosis microbe. Pseudotuberculocin differed in the antibacterial spectrum and morphology of the growth inhibition zones formed on the plates with the indicator strains from the pesticins produced by the strains of the plaque microbe of the marmot and sandword varieties respectively and the cultures of the plaque microbe from the Transcaucasian Upland, as well as from pesticins of the spheroplasts of these strains. Production of a pesticin differing from pesticins of the rod-like forms of these strains by an ability to inhibit the growth of the homologous indicators was shown in the spheroplasts of the plaque microbe of the marmot and sandword varieties. Sensitivity of the plaque microbe strains of the marmot and sandword varieties to the pesticins of the plaque microbe strains and pseudotuberculocin was noted. With an account of the difference in the activity of the tested pesticins and pseudotuberculocin against the strains of the Frederic collection it is recommended to use this property for identifications of pesticins and pseudotuberculocin.
在啮齿动物假结核微生物菌株的原生质体中发现了产生杆菌素的能力。作者将其命名为假结核菌素。在假结核微生物的原始菌株中未检测到杆菌素的产生。假结核菌素在抗菌谱以及在含有指示菌株的平板上形成的生长抑制区形态方面,与分别由旱獭和沙鼠品种的鼠疫微生物菌株产生的杀鼠菌素以及来自外高加索高地的鼠疫微生物培养物产生的杀鼠菌素不同,也与这些菌株原生质体的杀鼠菌素不同。在旱獭和沙鼠品种的鼠疫微生物的原生质体中显示出产生一种杀鼠菌素,该杀鼠菌素通过抑制同源指示菌生长的能力与这些菌株杆状形式的杀鼠菌素不同。注意到旱獭和沙鼠品种的鼠疫微生物菌株对鼠疫微生物菌株的杀鼠菌素和假结核菌素敏感。考虑到所测试的杀鼠菌素和假结核菌素对弗雷德里克菌库菌株活性的差异,建议利用这一特性来鉴定杀鼠菌素和假结核菌素。