脂肪细胞微环境：邻里街坊都在谈论温度。
Adipocyte Microenvironment: Everybody in the Neighborhood Talks about the Temperature.
机构信息
Joslin Diabetes Center, Section on Integrative Physiology and Metabolism, Harvard Medical School, Boston, MA, USA.
Joslin Diabetes Center, Section on Integrative Physiology and Metabolism, Harvard Medical School, Boston, MA, USA.
出版信息
Cell Metab. 2021 Jan 5;33(1):4-6. doi: 10.1016/j.cmet.2020.12.012.
Abstract
Adipose tissue is composed of a variety of cells distributed in different depots and playing various metabolic roles. In a recent issue of Nature, Sun et al. (2020) use snRNA-seq and functional studies to identify a population of adipocytes that can suppress the thermogenic activity of neighboring adipocytes by secretion of acetate.
摘要
脂肪组织由分布在不同部位的多种细胞组成，发挥着各种代谢作用。在最近的一期《自然》杂志上，Sun 等人（2020 年）利用 snRNA-seq 和功能研究鉴定出一种脂肪细胞群体，它可以通过分泌乙酸来抑制邻近脂肪细胞的产热活性。
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Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells.人类脂肪细胞亚型的多样化来源于转录上不同的间充质祖细胞。
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