Sigcha Luis, Pavón Ignacio, Costa Nélson, Costa Susana, Gago Miguel, Arezes Pedro, López Juan Manuel, Arcas Guillermo De
Instrumentation and Applied Acoustics Research Group (I2A2), ETSI Industriales, Universidad Politécnica de Madrid, Campus Sur UPM, Ctra. Valencia, Km 7, 28031 Madrid, Spain.
ALGORITMI Research Center, School of Engineering, University of Minho, 4800-058 Guimarães, Portugal.
Sensors (Basel). 2021 Jan 4;21(1):291. doi: 10.3390/s21010291.
Resting tremor in Parkinson's disease (PD) is one of the most distinctive motor symptoms. Appropriate symptom monitoring can help to improve management and medical treatments and improve the patients' quality of life. Currently, tremor is evaluated by physical examinations during clinical appointments; however, this method could be subjective and does not represent the full spectrum of the symptom in the patients' daily lives. In recent years, sensor-based systems have been used to obtain objective information about the disease. However, most of these systems require the use of multiple devices, which makes it difficult to use them in an ambulatory setting. This paper presents a novel approach to evaluate the amplitude and constancy of resting tremor using triaxial accelerometers from consumer smartwatches and multitask classification models. These approaches are used to develop a system for an automated and accurate symptom assessment without interfering with the patients' daily lives. Results show a high agreement between the amplitude and constancy measurements obtained from the smartwatch in comparison with those obtained in a clinical assessment. This indicates that consumer smartwatches in combination with multitask convolutional neural networks are suitable for providing accurate and relevant information about tremor in patients in the early stages of the disease, which can contribute to the improvement of PD clinical evaluation, early detection of the disease, and continuous monitoring.
帕金森病(PD)中的静止性震颤是最具特征性的运动症状之一。适当的症状监测有助于改善管理和医疗治疗,并提高患者的生活质量。目前,震颤是在临床预约期间通过体格检查进行评估的;然而,这种方法可能具有主观性,并且不能代表患者日常生活中症状的全貌。近年来,基于传感器的系统已被用于获取有关该疾病的客观信息。然而,这些系统中的大多数都需要使用多个设备,这使得它们在门诊环境中难以使用。本文提出了一种新颖的方法,利用消费级智能手表的三轴加速度计和多任务分类模型来评估静止性震颤的幅度和稳定性。这些方法用于开发一个系统,以在不干扰患者日常生活的情况下进行自动且准确的症状评估。结果表明,与临床评估中获得的结果相比,从智能手表获得的幅度和稳定性测量结果高度一致。这表明消费级智能手表与多任务卷积神经网络相结合适用于为疾病早期阶段的患者提供有关震颤的准确且相关的信息,这有助于改善PD临床评估、疾病的早期检测以及持续监测。