Pan Yufang, Hu Fan, Yu Chen, Li Chenjie, Huang Teng, Hu Hanhua
Key Laboratory of Algal Biology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
School of Foreign Languages, China University of Geosciences, Wuhan, China.
Front Plant Sci. 2020 Dec 17;11:589026. doi: 10.3389/fpls.2020.589026. eCollection 2020.
Diatoms can accumulate high levels of triacylglycerols (TAGs) under nitrogen depletion and have attracted increasing attention as a potential system for biofuel production. In , a model diatom, about 40% of lipid is synthesized from the breakdown of cellular components under nitrogen starvation. Our previous studies indicated that carbon skeletons from enhanced branched-chain amino acid (BCAA) degradation under nitrogen deficiency contribute to TAG biosynthesis in . In this review, we outlined the catabolic pathways of all 20 amino acids based on the genome, transcriptome, proteome, and metabolome data. The contribution of these amino acid catabolic pathways to TAG accumulation was also analyzed.
硅藻在氮缺乏条件下能积累高水平的三酰甘油（TAGs），作为一种潜在的生物燃料生产系统，已受到越来越多的关注。在一种模式硅藻中，约40%的脂质是在氮饥饿条件下由细胞成分的分解合成的。我们之前的研究表明，氮缺乏时增强的支链氨基酸（BCAA）降解产生的碳骨架有助于[该模式硅藻]中TAG的生物合成。在这篇综述中，我们基于基因组、转录组、蛋白质组和代谢组数据概述了所有20种氨基酸的分解代谢途径。还分析了这些氨基酸分解代谢途径对TAG积累的贡献。
