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蛇毒药物注射中胚层疗法治疗手部湿疹:两例报告

Mesotherapy with Snake Venom Pharmacopuncture to Treat Hand Eczema: Two Cases Report.

作者信息

Kim Sungha, Lee Jinbok, Shin Minseop

机构信息

Department of Clinical Research, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.

Spine Care Korean Medicine Clinic, Jeonju, Republic of Korea.

出版信息

J Pharmacopuncture. 2020 Dec 31;23(4):273-276. doi: 10.3831/KPI.2020.23.4.273.

DOI:10.3831/KPI.2020.23.4.273
PMID:33408903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7772079/
Abstract

Hand eczema is a recurrent and resistant disease that seriously affects the quality of life of patients; currently, there are no ideal treatments for hand eczema. Here, we describe two patients who presented with hand eczema to illustrate the potential efficacy of mesotherapy with snake venom pharmacopuncture (SVP). A 23-year-old woman (Case 1) and a 47-year-old woman (Case 2) presented to the clinic with symptoms of pruritic rash, blisters, and itchiness on both the hands and the left hand, respectively. Both patients were diagnosed with hand eczema based on the physical examination of blisters and redness only on the hands. The patients underwent 1 month (Case 1) and 1 week (Case 2) of mesotherapy with SVP. After treatment, the lesions completely improved and did not recur at 1 year of follow-up. These outcomes suggest that mesotherapy with SVP may be effective for the resolution of hand eczema; however, further research is needed to confirm these findings.

摘要

手部湿疹是一种反复发作且难以治愈的疾病,严重影响患者的生活质量;目前,尚无针对手部湿疹的理想治疗方法。在此,我们描述两名患有手部湿疹的患者,以说明蛇毒药物注射中医疗法(SVP)的潜在疗效。一名23岁女性(病例1)和一名47岁女性(病例2)分别因双手出现瘙痒性皮疹、水疱和瘙痒症状以及左手出现上述症状前来就诊。仅根据手部水疱和发红的体格检查,两名患者均被诊断为手部湿疹。两名患者分别接受了为期1个月(病例1)和1周(病例2)的SVP中医疗法治疗。治疗后,皮损完全改善,随访1年未复发。这些结果表明,SVP中医疗法可能有效治疗手部湿疹;然而,需要进一步研究来证实这些发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd83/7772079/ea09ef3bdb00/JoP-23-273-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd83/7772079/1f22b1fc7bbb/JoP-23-273-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd83/7772079/ea09ef3bdb00/JoP-23-273-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd83/7772079/1f22b1fc7bbb/JoP-23-273-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd83/7772079/ea09ef3bdb00/JoP-23-273-f2.jpg

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本文引用的文献

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Toxins (Basel). 2019 Sep 25;11(10):564. doi: 10.3390/toxins11100564.
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Mesotherapy: Safety profile and management of complications.中胚层疗法:安全性概况及并发症处理
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A Case Series of Snake Venom Pharmacopuncture for Chemotherapy-Induced Peripheral Neuropathy: A Retrospective Observational Study.蛇毒药物穴位注射治疗化疗所致周围神经病变的病例系列:一项回顾性观察研究
J Pharmacopuncture. 2017 Dec;20(4):280-286. doi: 10.3831/KPI.2017.20.034. Epub 2017 Nov 13.
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Mesotherapy, Microneedling, and Chemical Peels.中胚层疗法、微针疗法和化学换肤术。
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A Severe Case of Recalcitrant Pompholyx.一例严重的顽固性汗疱疹
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The key role of aquaporin 3 and aquaporin 10 in the pathogenesis of pompholyx.水通道蛋白3和水通道蛋白10在汗疱疹发病机制中的关键作用。
Med Hypotheses. 2015 May;84(5):498-503. doi: 10.1016/j.mehy.2015.02.006. Epub 2015 Feb 11.
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Hand eczema.手部湿疹。
N Engl J Med. 2012 Nov 8;367(19):1829-37. doi: 10.1056/NEJMcp1104084.
8
Pompholyx: a review of clinical features, differential diagnosis, and management.水疱性湿疹:临床特征、鉴别诊断及治疗的综述。
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Pompholyx: what's new?汗疱疹:有什么新进展?
Expert Opin Investig Drugs. 2008 Jun;17(6):897-904. doi: 10.1517/13543784.17.6.897.
10
No eczema without keratinocyte death.没有角质形成细胞死亡就没有湿疹。
J Clin Invest. 2000 Jul;106(1):9-10. doi: 10.1172/JCI10438.