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生活方式和饮食因素对脑肿瘤发生发展的影响。

Effect of lifestyle and dietary factors in the development of brain tumors.

作者信息

Bansal Nandini, Dawande Pratibha, Shukla Samarth, Acharya Sourya

机构信息

Medical Intern, Department of Medicine, Jawaharlal Nehru Medical College, Sawangi, Wardha, Maharashtra, India.

Associate Professor, Department of Pathology, Jawaharlal Nehru Medical College, Sawangi, Wardha, Maharashtra, India.

出版信息

J Family Med Prim Care. 2020 Oct 30;9(10):5200-5204. doi: 10.4103/jfmpc.jfmpc_640_19. eCollection 2020 Oct.

Abstract

INTRODUCTION

A brain tumor occurs when neurons are mutated and thus abnormal cells are formed. Glioma and meningioma are the two most common types, comprising approximately 75% of all brain tumors. The incidence rate of all primary brain tumors was 15.80/100,000 person-years in females and 14.33/100,000 person-years in males. An association of higher risk of brain tumors in adults with cured meat and fruit/vegetable consumption, the primary source of dietary N-nitroso compounds, is seen. Cigarette smoking is a major source of chemical carcinogens. The present study aimed at determining the effects of lifestyle and dietary habits in the development of brain tumor.

METHODS

The study aimed at the assessment of various dietary factors, lifestyle, and occupational and personal habits in patients diagnosed with brain tumor in a rural tertiary health-care hospital, using a structured questionnaire and statistical analysis.

RESULTS

It was observed that - (1) people with stressful, sedentary lifestyle and wrong diet and those addicted to alcohol consumption and the habit of cigarette smoking have higher risk of brain tumors; (2) males are more prone to brain tumors; and (3) among subtypes, majority had glioblastoma and the least had meningioma and opdivoglioblastoma and according to location, majority had cerebellopontine angle tumor and the least had left thalamic glioma and multicentric glioma. Primary care to preoperative brain tumor patients should be given in terms of preventing exposure to radiations, avoiding cigarette smoking, providing healthy diet, and avoiding chronic stress and environmental pollution and postoperative patients should be taken care including avoiding infections by maintaining proper hygiene and providing healthy diet for their speedy recovery.

CONCLUSION

People with stressful life condition, wrong diet, and sedentary lifestyle and those addicted to alcohol, with the habit of cigarette smoking, have higher risk of brain tumors. Males are more prone to brain tumors.

摘要

引言

当神经元发生突变并由此形成异常细胞时,就会发生脑肿瘤。胶质瘤和脑膜瘤是两种最常见的类型,约占所有脑肿瘤的75%。所有原发性脑肿瘤的发病率在女性中为15.80/10万人口年,在男性中为14.33/10万人口年。已发现成人脑肿瘤风险较高与食用腌制肉类和水果/蔬菜有关,而这些是膳食N-亚硝基化合物的主要来源。吸烟是化学致癌物的主要来源。本研究旨在确定生活方式和饮食习惯对脑肿瘤发生发展的影响。

方法

本研究旨在通过结构化问卷和统计分析,评估一家农村三级医疗保健医院中被诊断患有脑肿瘤的患者的各种饮食因素、生活方式以及职业和个人习惯。

结果

观察到 - (1)生活压力大、久坐不动、饮食不当以及酗酒和吸烟成瘾的人患脑肿瘤的风险更高;(2)男性更容易患脑肿瘤;(3)在亚型中,大多数患有胶质母细胞瘤,最少的是脑膜瘤和少突胶质母细胞瘤,按部位来看,大多数患有桥小脑角肿瘤,最少的是左侧丘脑胶质瘤和多中心胶质瘤。对于术前脑肿瘤患者,应从预防辐射暴露、避免吸烟、提供健康饮食以及避免慢性压力和环境污染等方面给予初级护理,对于术后患者,应进行护理,包括通过保持适当卫生避免感染,并提供健康饮食以促进其快速康复。

结论

生活条件压力大、饮食不当、久坐不动以及酗酒、吸烟成瘾的人患脑肿瘤的风险更高。男性更容易患脑肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d1a/7773078/6706c0ba70a8/JFMPC-9-5200-g001.jpg

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