Department of Ophthalmology, The University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Jpn J Ophthalmol. 2021 May;65(3):402-408. doi: 10.1007/s10384-020-00806-4. Epub 2021 Jan 7.
To compare 12-month clinical results of spatula-shaped and dual-blade microhooks ab interno trabeculotomy with phacoemulsification.
Retrospective comparative study.
We conducted a retrospective chart review of Japanese open-angle glaucoma patients who underwent ab interno trabeculotomy with phacoemulsification with a 12-month follow-up. Two types of trabecular hook were used: the spatula-shaped Tanito Trabeculotomy ab interno Micro-hook and the Kahook Dual Blade. Changes in intraocular pressure (IOP) and medication scores comprised the main outcome metrics. We also analyzed and compared patient demographics and the occurrence of complications.
Trabeculotomy was performed using a spatula-shaped hook in 17 eyes and a dual-blade hook in 15 eyes. Significant reductions in IOP (p < 0.001) and medication scores (p < 0.001) were noted in both groups after the 1-month time point. The percentage changes of IOP from baseline at each time point were not significantly different between groups, though there was a significant difference in medication scores at 12 months (p = 0.0192). Postoperative complications occurred similarly in both groups; one case in the dual-blade group required additional filtration surgery.
Ab interno trabeculotomy with phacoemulsification was effective in lowering IOP both with spatula-shaped and with double-blade microhooks. At 12 months more medications were used postoperatively in the spatula-shaped microhook group; however, the reductions in the medication scores from baseline were statistically significant in both groups.
比较匙形和双刀片微钩内切开术联合超声乳化术治疗 12 个月的临床效果。
回顾性比较研究。
我们对接受超声乳化术联合内切开术的日本开角型青光眼患者进行了回顾性图表分析,随访时间为 12 个月。使用了两种类型的小梁钩:匙形 Tanito 小梁内切开微钩和 Kahook 双刀片。主要观察指标为眼压(IOP)和药物评分的变化。我们还分析和比较了患者的人口统计学特征和并发症的发生情况。
17 只眼采用匙形钩进行内切开术,15 只眼采用双刀片钩。两组患者在术后 1 个月时,IOP(p<0.001)和药物评分(p<0.001)均显著降低。两组在各个时间点的眼压从基线的百分比变化没有显著差异,但在 12 个月时药物评分有显著差异(p=0.0192)。两组术后并发症发生率相似;双刀片组有 1 例需要额外的滤过手术。
超声乳化术联合内切开术联合使用匙形和双刀片微钩均可有效降低眼压。在 12 个月时,匙形微钩组术后使用的药物更多;然而,两组的药物评分从基线的降低均具有统计学意义。