Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Department of Nutrition and Food Technology, Faculty of Agriculture, Jordan University of Science and Technology, Irbid, 22110, Jordan.
BMC Oral Health. 2021 Jan 7;21(1):21. doi: 10.1186/s12903-020-01349-3.
Sleep bruxism may result in deleterious effects including loss of tooth enamel, fracture of teeth or restorations, teeth hypersensitivity or pain, and headache. The aim was to study the link between sleep bruxism, low serum vitamin D, low consumption of dietary calcium, psychological symptoms, and frequent headache.
This case-controlled study included 50 individuals with sleep bruxism and 50 age and gender matched controls. 25-hydroxyvitamin D was measured in serum. Hospital Anxiety and Depression Scale was used to measure anxiety and depression. Data about dietary calcium and frequent headache were self-reported.
Participants with sleep bruxism had lower 25-hydroxyvitamin D and higher scores of anxiety and depression compared to controls (p < 0.05). Vitamin D deficiency, abnormal scores of anxiety and depression, low calcium consumption (< 323 mg/day), and frequent headache were reported in higher % of individuals with sleep bruxism compared to controls (p < 0.05). Binary logistic regression showed that sleep bruxism was significantly associated with vitamin D deficiency (OR = 6.66, p = 0.02), low consumption of dietary calcium (OR = 5.94, p = 0.01), and frequent headache (OR = 9.24, p < 0.001). Multiple linear regression showed that anxiety was significantly associated with decreased 25-hydroxyvitamin D (p = 0.03), increased scores of depression (p < 0.001) and female sex (p = 0.01). Binary logistic regression also showed that frequent headache was significantly associated with sleep bruxism (OR = 5.51, p < 0.01).
Sleep bruxism was associated with vitamin D deficiency and low consumption of calcium and was also associated with increased scores of anxiety and depression. Further investigations should be performed to check if vitamin D and calcium supplementation could relieve sleep bruxism.
睡眠磨牙症可能会导致有害影响，包括牙釉质丧失、牙齿或修复体断裂、牙齿过敏或疼痛以及头痛。目的是研究睡眠磨牙症、血清维生素 D 水平低、膳食钙摄入量低、心理症状与频繁头痛之间的联系。
本病例对照研究纳入了 50 名睡眠磨牙症患者和 50 名年龄和性别匹配的对照者。检测血清 25-羟维生素 D。采用医院焦虑抑郁量表评估焦虑和抑郁。关于膳食钙和频繁头痛的数据由自我报告获得。
与对照组相比，睡眠磨牙症患者的血清 25-羟维生素 D 水平更低，焦虑和抑郁评分更高（p<0.05）。与对照组相比，更多的磨牙症患者存在维生素 D 缺乏、焦虑和抑郁评分异常、钙摄入量低（<323mg/天）和频繁头痛（p<0.05）。二元逻辑回归显示，睡眠磨牙症与维生素 D 缺乏（OR=6.66，p=0.02）、膳食钙摄入不足（OR=5.94，p=0.01）和频繁头痛（OR=9.24，p<0.001）显著相关。多元线性回归显示，焦虑与血清 25-羟维生素 D 降低显著相关（p=0.03），与抑郁评分增加显著相关（p<0.001），与女性性别显著相关（p=0.01）。二元逻辑回归还显示，频繁头痛与睡眠磨牙症显著相关（OR=5.51，p<0.01）。
睡眠磨牙症与维生素 D 缺乏和钙摄入不足有关，且与焦虑和抑郁评分增加有关。应进一步开展研究，以评估补充维生素 D 和钙是否可以缓解睡眠磨牙症。
