Ritvo E R, Creel D, Realmuto G, Crandall A S, Freeman B J, Bateman J B, Barr R, Pingree C, Coleman M, Purple R
Division of Mental Retardation, UCLA School of Medicine.
Am J Psychiatry. 1988 Feb;145(2):229-32. doi: 10.1176/ajp.145.2.229.
The authors recorded electroretinograms for 27 autistic patients and 20 age- and sex-matched healthy volunteers. Thirteen (48%) of the autistic patients demonstrated subnormal b-wave amplitudes, which may indicate abnormal retinal function. One patient was tested serially at two sites; his low b-wave amplitude did not vary over time or between the two sites. If this retinal finding can be confirmed at other laboratories and in larger samples of autistic patients, it might provide a marker for a specific subtype of autism.
作者为27名自闭症患者以及20名年龄和性别匹配的健康志愿者记录了视网膜电图。13名（48%）自闭症患者的b波振幅低于正常水平，这可能表明视网膜功能异常。一名患者在两个地点进行了连续测试；他较低的b波振幅在不同时间以及两个地点之间均未发生变化。如果这一视网膜检查结果能够在其他实验室以及更大规模的自闭症患者样本中得到证实，那么它可能为自闭症的一种特定亚型提供一个标志物。
