Fekete Helga, Guillemin Francis, Pallagi Edina, Fekete Róbert, Lippai Zoltán, Luterán Ferenc, Tóth István, Tóth Kálmán, Vallata Amandine, Varjú Cecília, Csóka Ildiko
Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Faculty of Pharmacy, Szeged, Hungary.
University of Lorraine, University Paris Descartes, Nancy, France.
Ther Adv Musculoskelet Dis. 2020 Dec 17;12:1759720X20959570. doi: 10.1177/1759720X20959570. eCollection 2020.
At least 17% of the population suffers from osteoarthritis (OA) in Hungary, according to the European Health Interview Survey. In Hungary, until now there was no OA-specific questionnaire available for the lower limb, in order to monitor the health-related quality of life (HRQoL). This gap gave the relevance of this research. The aim of the study was to perform the Hungarian cross-cultural adaptation and validation of the French-developed Osteoarthritis Knee and Hip Quality of Life (OAKHQoL) questionnaire.
The five-step translation procedure of the original OAKHQoL was performed by the expert panel and the translators. The created Hungarian version (OAKHQoL-HUN) was tested in six different geographical areas of Hungary. The validity and the reliability of this adapted tool was analyzed by our research group.
A total of 99 patients completed the questionnaires (78 women and 21 men), with the average age of 66.6 years (standard deviation (SD) 12.1), living with OA for more than 10 years. Excellent internal consistency was observed in the following domains: physical activity (α = 0.93), mental health (α = 0.91) and pain (α = 0.89). Good correlation was determined between physical subscales ( = 0.615-0.676) and mental subscales ( = 0.633-0.643) compared to generic quality of life instruments (World Health Organization Quality of life - BREF questionnaire and EQ-5D-3L).
The OAKHQoL-HUN is the first valid and reliable tool for measuring the Hungarian lower limb OA patients' quality of life.
This study is registered (24950-3/2016/EKU) by the National Ethics Committee: the Hungarian Medical Research Council.
根据欧洲健康访谈调查，匈牙利至少17%的人口患有骨关节炎（OA）。在匈牙利，迄今为止尚无专门用于下肢骨关节炎的问卷，以便监测与健康相关的生活质量（HRQoL）。这一差距使得本研究具有相关性。本研究的目的是对法国开发的骨关节炎膝髋关节生活质量（OAKHQoL）问卷进行匈牙利语跨文化调适和验证。
由专家小组和翻译人员对原始OAKHQoL进行五步翻译程序。创建的匈牙利语版本（OAKHQoL-HUN）在匈牙利六个不同地理区域进行了测试。我们的研究小组分析了该调适工具的效度和信度。
共有99名患者完成了问卷（78名女性和21名男性），平均年龄66.6岁（标准差（SD）12.1），患骨关节炎超过10年。在以下领域观察到了出色的内部一致性：身体活动（α = 0.93）、心理健康（α = 0.91）和疼痛（α = 0.89）。与通用生活质量工具（世界卫生组织生活质量简表问卷和EQ-5D-3L）相比，身体子量表（= 0.615 - 0.676）和心理子量表（= 0.633 - 0.643）之间具有良好的相关性。
OAKHQoL-HUN是首个用于测量匈牙利下肢骨关节炎患者生活质量的有效且可靠的工具。
本研究已由国家伦理委员会：匈牙利医学研究理事会注册（24950 - 3/2016/EKU）。
