IMDEA Energy, Biotechnological Processes Unit, Av. Ramón de la Sagra, 29835 Móstoles, Madrid, Spain.
IMDEA Energy, Biotechnological Processes Unit, Av. Ramón de la Sagra, 29835 Móstoles, Madrid, Spain.
Bioresour Technol. 2021 Mar;323:124612. doi: 10.1016/j.biortech.2020.124612. Epub 2020 Dec 25.
Microbial lipids have recently drawn a lot of attention as renewable sources for biochemicals production. Strong research efforts have been addressed to efficiently use organic wastes as carbon source for microbial lipids, which would definitively increase the profitability of the production process and boost a bio-based economy. This review compiles interesting traits of oleaginous microorganisms and highlights current trends on microbial- and process-oriented approaches to maximize microbial oil production from inexpensive substrates like lignocellulosic sugars, volatile fatty acids and glycerol. Furthermore, downstream processes such as cell harvesting or lipid extraction, that are decisive for the cost-effectiveness of the process, are discussed. To underpin microbial oils within the so demanded circular economy, associated challenges, recent advances and possible industrial applications that are also identified in this review.
微生物油脂作为生物化学制品生产的可再生资源，近年来引起了广泛关注。为了有效利用有机废物作为微生物油脂的碳源，已经进行了大量的研究工作，这将极大地提高生产过程的盈利能力，并推动生物基经济的发展。本综述总结了产油微生物的有趣特性，并强调了当前微生物和面向过程的方法的最新趋势，以最大限度地从木质纤维素糖、挥发性脂肪酸和甘油等廉价基质中生产微生物油脂。此外，还讨论了对工艺成本效益具有决定性影响的下游工艺，如细胞收获或油脂提取。为了在需求旺盛的循环经济中支持微生物油脂，本文还讨论了相关挑战、最新进展和可能的工业应用。
