Wang Guanjun, Shen Lida, Zhao Jianfeng, Liang Huixin, Xie Deqiao, Tian Zongjun, Wang Changjiang
College of Mechanical and Electrical Engineering, Nanjing University of Aeronautics and Astronautics, 29 Yudao Street, Nanjing 210016, PR China.
Suzhou Kangli Orthopedics Instrument Co. Ltd., Luyuan Tangqiao Town, Zhangjiagang Suzhou, 215600, PR China.
ACS Biomater Sci Eng. 2018 Feb 12;4(2):719-727. doi: 10.1021/acsbiomaterials.7b00916. Epub 2018 Jan 26.
Adjustment of the mechanical properties (apparent elastic modulus and compressive strength) in porous scaffolds is important for artificial implants and bone tissue engineering. In this study, a top-down design method based on Voronoi-Tessellation was proposed. This method was successful in obtaining the porous structures with specified and functionally graded porosity. The porous specimens were prepared by selective laser melting technology. Quasi-static compressive tests were conducted as well. The experiment results revealed that the mechanical properties were affected by both porosity and irregularity. The irregularity coefficient proposed in this study can achieve good accommodation and balance of "irregularity" and "controllability". The method proposed in this study provides an efficient approach for the bionic design and topological optimization of scaffolds.
调整多孔支架的力学性能（表观弹性模量和抗压强度）对于人工植入物和骨组织工程至关重要。在本研究中，提出了一种基于Voronoi镶嵌的自上而下设计方法。该方法成功获得了具有特定和功能梯度孔隙率的多孔结构。通过选择性激光熔化技术制备了多孔试样。还进行了准静态压缩试验。实验结果表明，力学性能受孔隙率和不规则性的影响。本研究提出的不规则系数能够很好地兼顾“不规则性”和“可控性”。本研究提出的方法为支架的仿生设计和拓扑优化提供了一种有效途径。
