Centre for Crop Science, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, Brisbane, QLD, 4072, Australia.
Theor Appl Genet. 2021 Jun;134(6):1691-1709. doi: 10.1007/s00122-020-03764-0. Epub 2021 Jan 8.
Integrating CRISPR/Cas9 genome editing into modern breeding programs for crop improvement in cereals. Global climate trends in many agricultural regions have been rapidly changing over the past decades, and major advances in global food systems are required to ensure food security in the face of these emerging challenges. With increasing climate instability due to warmer temperatures and rising CO levels, the productivity of global agriculture will continue to be negatively impacted. To combat these growing concerns, creative approaches will be required, utilising all the tools available to produce more robust and tolerant crops with increased quality and yields under more extreme conditions. The integration of genome editing and transgenics into current breeding strategies is one promising solution to accelerate genetic gains through targeted genetic modifications, producing crops that can overcome the shifting climate realities. This review focuses on how revolutionary genome editing tools can be directly implemented into breeding programs for cereal crop improvement to rapidly counteract many of the issues affecting agriculture production in the years to come.
将 CRISPR/Cas9 基因组编辑技术整合到现代谷物改良育种计划中。在过去几十年中,许多农业地区的全球气候趋势迅速变化,需要在全球粮食系统方面取得重大进展,以应对这些新出现的挑战。由于温度升高和 CO2 水平上升导致气候不稳定加剧,全球农业的生产力将继续受到负面影响。为了解决这些日益严重的问题,需要采用创造性的方法,利用所有可用的工具来生产更具弹性和耐受性的作物,在更极端的条件下提高质量和产量。将基因组编辑和转基因技术纳入当前的育种策略是加速遗传增益的一种有前途的方法,通过靶向基因修饰来生产能够克服不断变化的气候现实的作物。本综述重点介绍了如何将革命性的基因组编辑工具直接应用于谷物改良的育种计划中,以迅速应对未来几年影响农业生产的许多问题。