Guha Bishwajit, Arman Mohammad, Islam Mohammad Nazmul, Tareq Syed Mohammed, Rahman Md Masudur, Sakib Shahenur Alam, Mutsuddy Rahul, Tareq Abu Montakim, Emran Talha Bin, Alqahtani Ali M
Department of Pharmacy, Southern University Bangladesh, 739/A Mehedibag Road, Chittagong 4000, Bangladesh.
Department of Pharmacy, International Islamic University Chittagong, Chittagong 4318, Bangladesh.
Saudi J Biol Sci. 2021 Jan;28(1):183-190. doi: 10.1016/j.sjbs.2020.09.037. Epub 2020 Sep 24.
and both is an ethnomedicinally important Asian herb that has been known for numerous healing activity of tribal people. The present research aims to investigate the phytochemical analysis with , possibilities of the soluble ethanol extract of root (EEMLR) and leaves (EEQGL) by an experimental approach. The plant extract of EEMLR and EEQGL was found secondary metabolites, notably steroids, glycosides, tannins, flavonoids, saponins, gums, and alkaloids. Additionally, the extract showed significant activity in antioxidant, antipyretic, anti-inflammatory, membrane stabilization, cytotoxic, thrombolytic, and analgesic activities while no response in antibacterial activity. Our findings reveal that soluble ethanol extract of EEMLR and EEQGL is safe, which can be an effective source for exploring new medicinal products. This research's outcomes may provide potentials for mitigating pyrexia, inflammation, pain, cellular toxicity, and coagulation.
两者都是亚洲重要的民族药用植物，部落居民知晓其多种治疗功效。本研究旨在通过实验方法对其根的可溶性乙醇提取物（EEMLR）和叶的可溶性乙醇提取物（EEQGL）进行植物化学分析，并探究其可能性。EEMLR和EEQGL的植物提取物被发现含有次生代谢产物，特别是类固醇、糖苷、单宁、黄酮类化合物、皂苷、树胶和生物碱。此外，提取物在抗氧化、解热、抗炎、膜稳定、细胞毒性、溶栓和镇痛活性方面表现出显著活性，而在抗菌活性方面无反应。我们的研究结果表明，EEMLR和EEQGL的可溶性乙醇提取物是安全的，可为探索新的药用产品提供有效来源。本研究结果可能为减轻发热、炎症、疼痛、细胞毒性和凝血提供潜力。
