Raglio Alfredo, Bellandi Daniele, Manzoni Luca, Grossi Enzo
Music Therapy Research Laboratory, Istituti Clinici Scientifici Maugeri IRCCS, Via Maugeri, 27100, Pavia, Italy.
Geriatric Department, Fondazione Istituto Ospedaliero di Sospiro, Sospiro, CR, Italy.
Neurol Sci. 2021 May;42(5):2103-2106. doi: 10.1007/s10072-020-04986-2. Epub 2021 Jan 11.
Literature showed the effects of music therapy on behavioral disturbances, cognitive functions, and on quality of life in people with dementia. Especially, relational active music therapy approach is oriented to reduce behavioral disturbances increasing communication, especially non-verbal communication.
This study aimed at exploring the connection between the baseline characteristics of responders and the positive outcome of the intervention, but also the close relationship between the behavioral disturbances and the core of the therapeutic intervention (the relationship/communication improvement).
Linear correlation index between input variables and the presence of a critical improvement of behavioral symptoms according Neuropsychiatric Inventory and a semantic connectivity map were used to determine, respectively, variables predictive of the response and complex connections between clinical variables and the relational nature of active music therapy intervention. The dataset was composed of 27 variables and 70 patients with a moderate-severe stage of dementia and behavioral disturbances.
The main predictive factor is the Barthel Index, followed by NPI and some of its sub-items (mainly, Disinhibition, Depression, Hallucinations, Irritability, Aberrant Motor Activity, and Agitation). Moreover, the semantic map underlines how the improvement in communication/relationship is directly linked to "responder" variable. "Responder" variable is also connected to "age," "Mini Mental State Examination," and sex ("female").
The study confirms the appropriateness of active music therapy in the reduction of behavioral disturbances and also highlights how unsupervised artificial neural networks models can support clinical practice in defining predictive factors and exploring the correlation between characteristics of therapeutic-rehabilitative interventions and related outcomes.
文献表明音乐疗法对痴呆症患者的行为障碍、认知功能和生活质量有影响。特别是,关系性主动音乐疗法旨在通过增加交流,尤其是非语言交流来减少行为障碍。
本研究旨在探索反应者的基线特征与干预积极结果之间的联系,以及行为障碍与治疗干预核心(关系/交流改善)之间的密切关系。
分别使用输入变量与根据神经精神科问卷得出的行为症状显著改善之间的线性相关指数以及语义连接图,来确定反应的预测变量以及临床变量与主动音乐疗法干预的关系性质之间的复杂联系。数据集由27个变量和70名患有中度至重度痴呆症和行为障碍的患者组成。
主要预测因素是巴氏指数,其次是神经精神科问卷及其一些子项目(主要是脱抑制、抑郁、幻觉、易怒、异常运动活动和激越)。此外,语义图强调了交流/关系的改善如何与“反应者”变量直接相关。“反应者”变量还与“年龄”、“简易精神状态检查表”和性别(“女性”)相关。
该研究证实了主动音乐疗法在减少行为障碍方面的适用性,还强调了无监督人工神经网络模型如何能够在定义预测因素以及探索治疗康复干预特征与相关结果之间的相关性方面支持临床实践。