Mayberry J F, Mayell M J
City Hospital, Nottingham.
Gut. 1988 Jan;29(1):90-3. doi: 10.1136/gut.29.1.90.
One hundred and twenty nine children under the age of 15 years were diagnosed as having achalasia in Britain and Ireland between 1976 and 1985 by 175 surgeons with an interest in paediatrics or oesophageal disease. The incidence in Eire was 0.31 cases/10(5) population/year and this was significantly higher than in England and Wales (0.1/10(5)/year), Scotland (0.06/10(5)/year/or Northern Ireland (0.02/10(5)/year). Details of age at diagnosis were only obtained for 36 of the 129 patients. The disease appeared to become commoner with increasing age but there is no evidence of a delay in diagnosis until early adulthood. Such a delay would not account for the apparent regional variations in incidence, as they have also been reported in adults. Southern Irish children are at greater risk of the disease than other children in the British Isles.
1976年至1985年间，在英国和爱尔兰，175名对儿科或食管疾病感兴趣的外科医生诊断出129名15岁以下儿童患有贲门失弛缓症。爱尔兰的发病率为0.31例/10⁵人口/年，显著高于英格兰和威尔士（0.1/10⁵/年）、苏格兰（0.06/10⁵/年）或北爱尔兰（0.02/10⁵/年）。在这129名患者中，仅获取到了36名患者的诊断年龄细节。该病似乎随着年龄增长而更为常见，但没有证据表明在成年早期之前存在诊断延迟。这种延迟并不能解释发病率明显的地区差异，因为成人中也有类似报道。爱尔兰南部儿童患该病的风险高于不列颠群岛的其他儿童。
