Shanmuganantha Lohashenpahan, Baharudin Azmi, Sulong Abu Bakar, Shamsudin Roslinda, Ng Min Hwei
Department of Tissue Engineering, National University of Malaysia, Selangor Darul Ehsan 56000, Malaysia.
Department of Orthopaedic and Traumatology, National University of Malaysia, Selangor Darul Ehsan 56000, Malaysia.
Materials (Basel). 2021 Jan 7;14(2):277. doi: 10.3390/ma14020277.
This literature review discusses the influence of titanium ceramic composites as a biomaterial towards the fabrication of implants for orthopedic applications. The concept of applying metal-ceramic composites enable many novel combinations in the design and fabrication of complex materials which enhances functionality to improve cell and tissue matrix interactions particularly in the formation of bone. Specific focus is placed on its plethora of materials selected from the metals and ceramic group and identifying the optimal combination that matches them. The prospect of wollastonite as the ceramic counterpart is also highlighted. In this review, we have highlighted the different fabrication methods for such metal-ceramic materials as well as the role that these hybrids play in an in vitro and in vivo environment. Its economic potential as a bone implant material is also discussed.
这篇文献综述讨论了钛陶瓷复合材料作为生物材料对骨科植入物制造的影响。应用金属陶瓷复合材料的概念使得在复杂材料的设计和制造中有许多新颖的组合，从而增强了功能，改善了细胞与组织基质的相互作用，特别是在骨形成方面。特别关注从金属和陶瓷组中选择的大量材料，并确定与之匹配的最佳组合。硅灰石作为陶瓷对应物的前景也得到了强调。在这篇综述中，我们强调了这种金属陶瓷材料的不同制造方法，以及这些复合材料在体外和体内环境中所起的作用。还讨论了其作为骨植入材料的经济潜力。
