Department of Conservative Dentistry and Endodontics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, JSS Medical Institutions Campus, Sri Shivarathreeshwara Nagar, Mysuru, Karnataka, India.
Indian J Dent Res. 2020 Sep-Oct;31(5):670-677. doi: 10.4103/ijdr.IJDR_735_17.
Erosion, a dynamic process with periods of demineralisation and remineralisation, has become a common problem in modern societies, owing to changes in life style and dietary habits. Although fluorides have been included in toothpastes that claim to prevent demineralisation and aid remineralisation, their ability to remineralise is limited by low concentration of calcium and phosphate ions available in saliva. Hence, a new paste based on casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF), nanohydroxyapatite and bioactive glass (BAG) were introduced.
To evaluate and compare the effects of BAG, nanohydroxyapatite and CPP-ACPF pastes on surface microhardness of demineralised enamel.
48 enamel specimens were randomly divided into five groups: Group I positive control - intact specimens and Group II - demineralised specimens. The test groups, Group III, IV and V, comprised CPP-ACPF, nanohydroxyapatite and BAG, respectively. The test specimens were demineralised with 0.1% citric acid followed by remineralisation using either of the three prepared slurries. The specimens were subjected to pH cycling regime for 15 times. The remineralisation potential of the specimens was studied by evaluating the surface microhardness. One specimen from each group was analysed under SEM. Data was tabulated and analysis performed by one way ANOVA and post hoc Scheffe test.
Statistically significant difference was found between the negative control and three test groups based on microhardness evaluation. Nanohydroxyapatite had the least remineralising potential as compared to CPP-ACPF and BAG.
Comparatively, BAG and CCP-ACPF paste showed better remineralising potential.
由于生活方式和饮食习惯的改变，侵蚀（一种具有脱矿和再矿化周期的动态过程）已成为现代社会的常见问题。尽管含氟牙膏已被添加到声称可预防脱矿和促进再矿化的牙膏中，但由于唾液中钙和磷酸盐离子的浓度低，其再矿化能力有限。因此，推出了一种基于酪蛋白磷酸肽-无定形磷酸钙氟化物（CPP-ACPF）、纳米羟基磷灰石和生物活性玻璃（BAG）的新型牙膏。
评估和比较 BAG、纳米羟基磷灰石和 CPP-ACPF 牙膏对脱矿釉质表面显微硬度的影响。
将 48 个釉质样本随机分为五组：I 组为阳性对照组 - 完整样本，II 组为脱矿样本。测试组 III、IV 和 V 分别由 CPP-ACPF、纳米羟基磷灰石和 BAG 组成。用 0.1%柠檬酸对测试样本进行脱矿处理，然后用三种准备好的糊剂中的任何一种进行再矿化。用 pH 循环法对样本进行 15 次循环。通过评估表面显微硬度来研究样本的再矿化潜力。从每组中取出一个样本进行 SEM 分析。对数据进行制表并采用单因素方差分析和事后 Scheffe 检验进行分析。
基于显微硬度评估，发现阴性对照组与三个测试组之间存在显著差异。与 CPP-ACPF 和 BAG 相比，纳米羟基磷灰石的再矿化潜力最小。
相比之下，BAG 和 CCP-ACPF 牙膏具有更好的再矿化潜力。
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