Tomczak Wirginia, Gryta Marek
Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, ul. Pułaskiego 10, 70-322 Szczecin, Poland.
Membranes (Basel). 2021 Jan 8;11(1):44. doi: 10.3390/membranes11010044.
In recent years, microfiltration (MF) has gained great interest as an excellent technique for clarification of biological suspensions. This paper addresses a direct comparison of efficiency, performance and susceptibility to cleaning of the ceramic and polymeric MF membranes applied for purification of 1,3-propanediol (1,3-PD) fermentation broths and suspensions of yeast . For this purpose, ceramic, titanium dioxide (TiO) based membranes and polypropylene (PP) membranes were used. It has been found that both TiO and PP membranes provide sterile permeate during filtration of 1,3-PD broths. However, the ceramic membrane, due to the smaller pore diameter, allowed obtaining a better quality permeate. All the membranes used were highly susceptible to fouling with the components of the clarified broths and yeast suspensions. The significant impact of the feed flow velocity and fermentation broth composition on the relative permeate flux has been demonstrated. Suitable cleaning agents with selected concentration and duration of action effectively cleaned the ceramic membrane. In turn, the use of aggressive cleaning solutions led to degradation of the PP membranes matrix. Findings of this study add to a growing body of literature on the use of ceramic and polypropylene MF membranes for the clarification of biological suspensions.
近年来，微滤（MF）作为一种用于澄清生物悬浮液的出色技术受到了广泛关注。本文直接比较了用于纯化1,3 - 丙二醇（1,3 - PD）发酵液和酵母悬浮液的陶瓷和聚合物微滤膜在效率、性能及清洗易感性方面的差异。为此，使用了陶瓷膜、二氧化钛（TiO₂）基膜和聚丙烯（PP）膜。研究发现，在过滤1,3 - PD发酵液时，TiO₂膜和PP膜均能提供无菌渗透液。然而，由于陶瓷膜孔径较小，其渗透液质量更佳。所有使用的膜都极易被澄清发酵液和酵母悬浮液中的成分污染。已证明进料流速和发酵液组成对相对渗透通量有显著影响。选用合适的清洗剂并控制其浓度和作用时间能有效清洗陶瓷膜。相反，使用腐蚀性强的清洗液会导致PP膜基质降解。本研究结果为有关使用陶瓷和聚丙烯微滤膜澄清生物悬浮液的文献增添了新内容。
