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阴离子间隙作为老年人隐匿性骨髓瘤的筛查方法。

The anion gap as a screening procedure for occult myeloma in the elderly.

作者信息

Flanagan N G, Ridway J C, Irving A G

机构信息

Department of Haematology, Victoria Hospital, Blackpool, Lancashire.

出版信息

J R Soc Med. 1988 Jan;81(1):27-8. doi: 10.1177/014107688808100112.

Abstract

Myeloma in the elderly can mimic many disorders, causing delay in diagnosis. In a retrospective study, the mean anion gap at presentation in 78 elderly patients with confirmed myeloma was found to be significantly less than that of aged-matched controls. It is suggested that estimation of the anion gap may be useful as a screening test, particularly as it has no intrinsic cost.

摘要

老年骨髓瘤可能会模仿多种病症,导致诊断延迟。在一项回顾性研究中,发现78例确诊骨髓瘤的老年患者就诊时的平均阴离子间隙显著低于年龄匹配的对照组。有人认为,阴离子间隙的评估作为一种筛查测试可能有用,特别是因为它没有内在成本。

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本文引用的文献

1
Multiple myeloma in a retirement area.退休人员聚居区的多发性骨髓瘤
Age Ageing. 1983 May;12(2):131-5. doi: 10.1093/ageing/12.2.131.
2
Multiple myeloma on the Fylde coast.菲尔德海岸的多发性骨髓瘤。
Br Med J (Clin Res Ed). 1984 Oct 20;289(6451):1075. doi: 10.1136/bmj.289.6451.1075.
4
Value of anion-gap determination in multiple myeloma.阴离子间隙测定在多发性骨髓瘤中的价值。
N Engl J Med. 1977 Apr 14;296(15):858-60. doi: 10.1056/NEJM197704142961507.
6
Multiple myeloma and the anion gap.多发性骨髓瘤与阴离子间隙
N Engl J Med. 1975 Mar 13;292(11):574-5. doi: 10.1056/NEJM197503132921107.
7
Anion gap in multiple myeloma.多发性骨髓瘤中的阴离子间隙
Acta Haematol. 1979;62(3):148-52. doi: 10.1159/000207561.

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