Flanagan N G, Ridway J C, Irving A G
Department of Haematology, Victoria Hospital, Blackpool, Lancashire.
J R Soc Med. 1988 Jan;81(1):27-8. doi: 10.1177/014107688808100112.
Myeloma in the elderly can mimic many disorders, causing delay in diagnosis. In a retrospective study, the mean anion gap at presentation in 78 elderly patients with confirmed myeloma was found to be significantly less than that of aged-matched controls. It is suggested that estimation of the anion gap may be useful as a screening test, particularly as it has no intrinsic cost.
老年骨髓瘤可能会模仿多种病症，导致诊断延迟。在一项回顾性研究中，发现78例确诊骨髓瘤的老年患者就诊时的平均阴离子间隙显著低于年龄匹配的对照组。有人认为，阴离子间隙的评估作为一种筛查测试可能有用，特别是因为它没有内在成本。
