Su Yingchao, Li Dayong, Su Yichang, Lu Chengjia, Niu Liyuan, Lian Jianshe, Li Guangyu
Key Laboratory of Automobile Materials, Ministry of Education, College of Materials Science and Engineering, Jilin University, 5988 Renmin Street, Changchun 130025, China.
Department of Material Engineer, Zhejiang Industry & Trade Vocational College,717 Fudong Street, Wenzhou 325003, China.
ACS Biomater Sci Eng. 2016 May 9;2(5):818-828. doi: 10.1021/acsbiomaterials.6b00013. Epub 2016 Apr 6.
The application of calcium phosphate reinforced magnesium matrix composites has not achieved the expected effect to control the degradation rate of magnesium so far. Therefore, in order to enhance the corrosion resistance and further develop the surface bioactivity of the composites to meet specific requirements of bone tissue engineering applications, biocompatible dicalcium phosphate dihydrate (DCPD) and hydroxyapatite (HA) coatings have been deposited on homemade HA/Mg composites using a simple conversion coating method and a subsequent alkali post-treatment, respectively. The conversion coating mechanism was studied by comparing coating processes on the composites, pure Mg, and an AZ60 Mg alloy. Electrochemical results showed that polarization resistance of the optimum DCPD and HA coatings was about 15 and 65 times higher than that of the composites, respectively. Immersion tests in simulated body fluid revealed that both coatings could supply improved corrosion resistance and biomineralization ability for the HA/Mg composites.
迄今为止，磷酸钙增强镁基复合材料的应用尚未达到控制镁降解速率的预期效果。因此，为了提高复合材料的耐腐蚀性并进一步开发其表面生物活性，以满足骨组织工程应用的特定要求，分别采用简单的转化涂层法和后续碱后处理工艺，在自制的HA/Mg复合材料上制备了生物相容性二水磷酸二钙（DCPD）和羟基磷灰石（HA）涂层。通过比较复合材料、纯镁和AZ60镁合金上的涂层工艺，研究了转化涂层机理。电化学结果表明，最佳DCPD涂层和HA涂层的极化电阻分别比复合材料高约15倍和65倍。在模拟体液中的浸泡试验表明，两种涂层都能提高HA/Mg复合材料的耐腐蚀性和生物矿化能力。
