Honarvar Behnam, Khaksar Elahe, Jafari Fatemeh, Zahedroozegar Mohammad Hassan, Amiri Sanaz
Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
School of Mathematics and Statistics, Carleton University, Ottawa, Ontario, Canada.
Dement Geriatr Cogn Dis Extra. 2020 Nov 16;10(3):143-153. doi: 10.1159/000511397. eCollection 2020 Sep-Dec.
BACKGROUND/AIMS: Quality of life (QOL) and Alzheimer disease (AD) among older people have been recognized as public health challenges. Here, we investigated the association between QOL and AD in the elders.
In this cross-sectional study, elderly people were selected from urban health centers (Shiraz, Iran) by multistage cluster random sampling and were interviewed using LEIPAD (for QOL) and Montreal Cognitive Assessment (for AD) questionnaires. The data was analyzed using Mplus (version 6.12) and IBM SPSS (version 25) software.
The participants consisted of 182 elderly with a mean age of 67 ± 5.05 years, and 95 (52.2%) of them were females. There were 161 (88.5%) and 130 (71.4%) cases educated up to 12 years and married, respectively. Furthermore, 46 (25.3%) had low-to-moderate QOL, and 132 (72.5%) were suspected to have AD. QOL was inversely associated with AD, and men (β = -0.310) were more affected than women (β = -0.290). AD (β = -0.298), age (β = -0.288), hypertension (β = -0.267), education (β = 0.260), and body mass index (β = -0.198) were determinants of QOL. Also, physical activity was indirectly associated with QOL (β = 0.076). AD was correlated with the cognitive functioning component of QOL ( = -0.72).
One elder out of 4, did not have desirable QOL and 3 elders out of 4 were suspected to have AD. AD can decrease QOL among the older people. Screening of the elders for AD is recommended to improve their QOL by health centers.
背景/目的：老年人的生活质量（QOL）和阿尔茨海默病（AD）已被视为公共卫生挑战。在此，我们调查了老年人中QOL与AD之间的关联。
在这项横断面研究中，通过多阶段整群随机抽样从城市健康中心（伊朗设拉子）选取老年人，并使用LEIPAD（用于QOL）和蒙特利尔认知评估（用于AD）问卷进行访谈。使用Mplus（版本6.12）和IBM SPSS（版本25）软件对数据进行分析。
参与者包括182名老年人，平均年龄为67±5.05岁，其中95名（52.2%）为女性。分别有161名（88.5%）和130名（71.4%）受教育年限达12年且已婚。此外，46名（25.3%）的QOL为低至中等，132名（72.5%）疑似患有AD。QOL与AD呈负相关，男性（β = -0.310）比女性（β = -0.290）受影响更大。AD（β = -0.298）、年龄（β = -0.288）、高血压（β = -0.267）、教育程度（β = 0.260）和体重指数（β = -0.198）是QOL的决定因素。此外，身体活动与QOL间接相关（β = 0.076）。AD与QOL的认知功能成分相关（= -0.72）。
四分之一的老年人QOL不理想，四分之三的老年人疑似患有AD。AD会降低老年人的QOL。建议健康中心对老年人进行AD筛查以改善他们的QOL。
