Nawej Tshikung Olivier, Buvelot Hélène, Calmy Alexandra, Cavassini Matthias
Unité VIH/SIDA, Service des maladies infectieuses, HUG, 1211 Genève 14.
Service des maladies infectieuses, CHUV, 1011 Lausanne.
Rev Med Suisse. 2021 Jan 13;17(720-1):95-101.
The current COVID-19 pandemic is the main topic of news worldwide by its magnitude and consequences across the entire planet. From a medical point of view, several risk factors for developing severe illness have been reported in the literature, notably an immunosuppressed status. For people living with HIV, several questions have been raised concerning not only their vulnerability, but also in relation to an eventual protection conferred by antiretroviral therapy. This article will address these two pandemics by looking at the potential impact of SARS-CoV-2 on people living with HIV and, in parallel, exploring similarities and differences in terms of treatment, potential for recovery, prevention and their impact on clinical research. We review also future novel therapies for the treatment of HIV.
当前的新冠疫情因其在全球范围内的规模和影响，成为世界各地新闻报道的主要话题。从医学角度来看，文献中已报道了一些导致重症的风险因素，尤其是免疫抑制状态。对于艾滋病毒感染者，人们不仅对他们的易感性提出了诸多问题，还涉及到抗逆转录病毒疗法可能提供的保护作用。本文将探讨这两种大流行病，研究新冠病毒对艾滋病毒感染者的潜在影响，同时探讨在治疗、康复潜力、预防以及对临床研究的影响等方面的异同。我们还将综述未来治疗艾滋病毒的新型疗法。
