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通过单纯低温保存小肠同种异体移植物12小时和24小时。使用环孢素后的存活率。

Twelve-hour and twenty four-hour preservation of small bowel allografts by simple hypothermia. Survival utilizing cyclosporine.

作者信息

Raju S, Fujiwara H, Lewin J R, Grogan J B

机构信息

University of Mississippi Medical Center, Department of Surgery, Jackson 39216-4505.

出版信息

Transplantation. 1988 Feb;45(2):290-3. doi: 10.1097/00007890-198802000-00007.

DOI:10.1097/00007890-198802000-00007
PMID:3344548
Abstract

Canine small bowel was harvested and stored by simple hypothermic technique. After 12- and 24-hr storage, respectively, the small bowel graft was allotransplanted into recipients. All animals receiving 12-hr stored grafts (n = 9) survived beyond 5 days. In the 24-hr storage group, 67% of the animals (n = 9) survived beyond 5 days. Successful storage for such extended periods by simple hypothermia has not been achieved previously. Donor pretreatment with antibiotics as well as extensive intraluminal irrigation of the harvested small bowel are considered to be important technical features in this successful preservation.

摘要

犬小肠采用简单低温技术进行采集和保存。分别在保存12小时和24小时后,将小肠移植物同种异体移植到受体中。所有接受保存12小时移植物的动物(n = 9)存活超过5天。在保存24小时的组中,67%的动物(n = 9)存活超过5天。此前尚未通过简单低温实现如此长时间的成功保存。供体用抗生素预处理以及对采集的小肠进行广泛的腔内冲洗被认为是这种成功保存的重要技术特点。

相似文献

1
Twelve-hour and twenty four-hour preservation of small bowel allografts by simple hypothermia. Survival utilizing cyclosporine.通过单纯低温保存小肠同种异体移植物12小时和24小时。使用环孢素后的存活率。
Transplantation. 1988 Feb;45(2):290-3. doi: 10.1097/00007890-198802000-00007.
2
Effect of cyclosporine on fresh and preserved orthotopic small bowel allografts.环孢素对新鲜及保存的原位小肠同种异体移植的影响。
P R Health Sci J. 1987 Dec;6(3):147-52.
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Failure of cyclosporine to prevent small bowel allograft rejection in pigs.环孢素未能预防猪小肠移植排斥反应。
J Surg Res. 1985 Jun;38(6):553-8. doi: 10.1016/0022-4804(85)90075-7.
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Structure and function of orthotopic small bowel allografts in rats treated with cyclosporine.
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Small bowel transplantation in the dog using cyclosporine.使用环孢素在犬类中进行小肠移植。
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Preservation of the pancreas for transplantation.用于移植的胰腺保存
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Successful canine small bowel preservation in simple cold storage for 48 hours using a dextran-40-based solution.使用基于右旋糖酐-40的溶液在简单冷藏条件下成功保存犬小肠48小时。
Transplant Proc. 1993 Feb;25(1 Pt 2):1576-9.

引用本文的文献

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Mucosal damage and recovery of the intestine after prolonged preservation and transplantation in dogs.犬长时间保存及移植后肠道的黏膜损伤与恢复
Transplantation. 2001 Jan 15;71(1):1-7. doi: 10.1097/00007890-200101150-00001.
2
The significance of cytological examination on reperfusion in rat small intestinal transplantation.大鼠小肠移植中再灌注的细胞学检查意义
Virchows Arch. 1995;427(1):71-6. doi: 10.1007/BF00203740.