Department of Neurology, University Hospital Essen (J.G., E.-E.D., M.J., C.K., D.M.H.), University of Duisburg-Essen, Germany.
Institute of Medical Sociology, Medical Faculty, Heinrich-Heine-University Düsseldorf, Germany (M.E.).
Stroke. 2021 Jan;52(2):735-747. doi: 10.1161/STROKEAHA.120.032070. Epub 2021 Jan 15.
The current coronavirus disease 2019 (COVID-19) pandemic represents a severe, life-changing event for people across the world. Life changes may involve job loss, income reduction due to furlough, death of a beloved one, or social stress due to life habit changes. Many people suffer from social isolation due to lockdown or physical distancing, especially those living alone and without family. This article reviews the association of life events and social isolation with cardiovascular disease, assembling the current state of knowledge for stroke and coronary heart disease. Possible mechanisms underlying the links between life events, social isolation, and cardiovascular disease are outlined. Furthermore, groups with increased vulnerability for cardiovascular disease following life events and social isolation are identified, and clinical implications of results are presented.
当前的 2019 年冠状病毒病（COVID-19）大流行是全世界人民面临的严重、改变生活的事件。生活变化可能包括失业、因休假而减少收入、心爱之人的去世，或因生活习惯改变而产生的社会压力。许多人因封锁或保持身体距离而遭受社会孤立，尤其是那些独居且没有家人的人。本文综述了生活事件和社会隔离与心血管疾病的关联，汇集了目前关于中风和冠心病的知识状况。概述了生活事件、社会隔离和心血管疾病之间联系的可能机制。此外，确定了生活事件和社会隔离后心血管疾病易感性增加的人群，并提出了结果的临床意义。
