Crisostomo E A, Duncan P W, Propst M, Dawson D V, Davis J N
Department of Medicine, Duke University Medical Center, Durham, NC.
Ann Neurol. 1988 Jan;23(1):94-7. doi: 10.1002/ana.410230117.
We conducted a double-blind pilot study of 8 patients with established cerebral infarction to evaluate the effect of a single dose of amphetamine on recovery of motor function using the Fugl-Meyer scale. Four patients received amphetamine; the rest were given placebo. All underwent a session of physical therapy. Patients treated with amphetamine obtained greater increments in motor scores than the controls. Along with animal studies, these findings may allow the development of a pharmacological approach to stroke rehabilitation.
我们对8例已确诊为脑梗死的患者进行了一项双盲试点研究，以使用Fugl-Meyer量表评估单剂量苯丙胺对运动功能恢复的影响。4例患者接受苯丙胺治疗；其余患者给予安慰剂。所有患者均接受了一期物理治疗。接受苯丙胺治疗的患者在运动评分上的增量高于对照组。连同动物研究，这些发现可能有助于开发一种用于中风康复的药理学方法。
