Bernstein E F, Dilley R B, Randolph H F
Division of Thoracic and Vascular Surgery, Scripps Clinic and Research Foundation, La Jolla, California 92037.
Ann Surg. 1988 Mar;207(3):318-22. doi: 10.1097/00000658-198803000-00016.
During the past decade, selective criteria for elective surgery for abdominal aortic aneurysms have been refined based on natural history and aneurysm expansion information. Using these criteria, contemporary preoperative preparation and newer intraoperative technical adjuncts, 123 consecutive patients underwent elective resection with 1 death (mortality rate: 0.8%). These include all patients operated on with both elective and urgent aneurysms at this institution since 1978, with the exception of those with frank rupture. Most importantly, however, the 5-year life-table survival of all of these patients (average age: 71.3 years, range 46-96 yr) was 72%, including both hospital and late mortality rates. More than half of the patients were over 70 years old (78 cases), with no hospital deaths and a 5-year life-table survival probability of 67%. For those under 70 years of age at the time of operation, the 5-year life-table probability of survival was 79%. We believe that these accomplishments were a direct result of an aggressive policy of screening for and selectively treating coronary disease and carotid stenosis preoperatively and the utilization of such intraoperative adjuncts as routine Swan-Ganz monitoring, autologous blood transfusion, the cell saver, and the frequent use of the tube grafting (50%). Thus, with proper selection, the outlook for the patient over 70 years old with an elective abdominal aortic aneurysm resection now approaches that of the normal population (67% vs. 69%).
在过去十年中,基于自然病史和动脉瘤扩张信息,腹主动脉瘤择期手术的选择标准得到了完善。利用这些标准、当代术前准备和更新的术中技术辅助手段,123例连续患者接受了择期切除术,1例死亡(死亡率:0.8%)。这包括自1978年以来在本机构接受择期和急诊动脉瘤手术的所有患者,但不包括那些有明显破裂的患者。然而,最重要的是,所有这些患者(平均年龄:71.3岁,范围46 - 96岁)的5年生命表生存率为72%,包括医院死亡率和晚期死亡率。超过一半的患者年龄超过70岁(78例),无医院死亡,5年生命表生存概率为67%。对于手术时年龄在70岁以下的患者,5年生命表生存概率为79%。我们认为,这些成就直接得益于术前积极筛查和选择性治疗冠心病和颈动脉狭窄的策略,以及术中使用常规Swan - Ganz监测、自体输血、细胞回收器和频繁使用管状移植物(50%)等辅助手段。因此,通过适当选择,70岁以上接受择期腹主动脉瘤切除术患者的预后现在已接近正常人群(67%对69%)。