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西澳大利亚腹主动脉瘤手术后的长期相对生存率:基于人群的研究。

Long term relative survival after surgery for abdominal aortic aneurysm in western Australia: population based study.

作者信息

Norman P E, Semmens J B, Lawrence-Brown M M, Holman C D

机构信息

University Department of Surgery, Fremantle Hospital, PO Box 480, Fremantle, Western Australia 6959, Australia.

出版信息

BMJ. 1998 Sep 26;317(7162):852-6. doi: 10.1136/bmj.317.7162.852.

Abstract

OBJECTIVE

To determine the long term relative survival of all patients who had surgery for abdominal aortic aneurysm in Western Australia during 1985-94.

DESIGN

Population based study.

SETTING

Western Australia.

SUBJECTS

All patients who had had surgery for abdominal aortic aneurysm in Western Australia during 1985-94.

MAIN OUTCOME MEASURES

Morbidity and mortality data of patients admitted and surgically treated for abdominal aortic aneurysm in Western Australia during 1985-94. Elective, ruptured, and acute non-ruptured cases were analysed separately. Independent analyses for sex and patients aged 80 years or more were also undertaken. Postoperative (>30 days) relative survival was assessed against age and sex matched controls.

RESULTS

Overall, 1475 (1257 men, 218 women) cases were identified. The crude five year survival after elective surgery, including deaths within 30 days of surgery, was 79% for both men and women. When compared with a matched population the five year relative survival after elective surgery was 94.9% (95% confidence interval 89.9% to 99.9%) for men but only 88.0% (76.3% to 99.7%) for women. The five year relative survival of those aged 80 years and over was good: 116.6% (89.1% to 144.0%) compared with 92.4% (87.7% to 97.0%) for those under 80 years of age (men and women combined). Cardiovascular disease caused 57.8% of the 341 deaths after 30 days.

CONCLUSION

In a condition such as abdominal aortic aneurysm, which occurs in elderly patients, relative survival is more clinically meaningful than crude survival. The five year relative survival in cases of elective and ruptured abdominal aortic aneurysm was better in men than in women. This is probably because of greater comorbidity in women with abdominal aortic aneurysm and this deserves more attention in the future. The long term survival outcome in octogenarians supports surgery in selected cases.

摘要

目的

确定1985 - 1994年期间在西澳大利亚州接受腹主动脉瘤手术的所有患者的长期相对生存率。

设计

基于人群的研究。

地点

西澳大利亚州。

研究对象

1985 - 1994年期间在西澳大利亚州接受腹主动脉瘤手术的所有患者。

主要观察指标

1985 - 1994年期间在西澳大利亚州因腹主动脉瘤入院并接受手术治疗的患者的发病率和死亡率数据。对择期、破裂和急性非破裂病例分别进行分析。还对性别和80岁及以上患者进行了独立分析。根据年龄和性别匹配的对照评估术后(>30天)相对生存率。

结果

共确定了1475例(1257例男性,218例女性)。择期手术后的粗五年生存率,包括手术30天内的死亡病例,男性和女性均为79%。与匹配人群相比,择期手术后男性的五年相对生存率为94.9%(95%置信区间89.9%至99.9%),而女性仅为88.0%(76.3%至99.7%)。80岁及以上患者的五年相对生存率良好:为116.6%(89.1%至144.0%),而80岁以下患者(男性和女性合计)为92.4%(87.7%至97.0%)。心血管疾病导致30天后341例死亡中的57.8%。

结论

在腹主动脉瘤这种多见于老年患者的疾病中,相对生存率比粗生存率在临床上更具意义。择期和破裂性腹主动脉瘤病例的五年相对生存率男性高于女性。这可能是因为腹主动脉瘤女性患者的合并症更多,未来值得更多关注。八十多岁患者的长期生存结果支持在特定病例中进行手术。

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