Guangdong Key Laboratory of Environmental Pollution and Health, School of Environment, Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality, Jinan University, Guangzhou 511443, China.
Guangdong Key Laboratory of Environmental Pollution and Health, School of Environment, Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality, Jinan University, Guangzhou 511443, China.
J Hazard Mater. 2021 Jun 5;411:125073. doi: 10.1016/j.jhazmat.2021.125073. Epub 2021 Jan 7.
Food intake has been identified as a major route for infants to short- and medium-chain chlorinated paraffins (SCCPs and MCCPs, respectively), but evaluations of SCCPs and MCCPs exposure for infants via dietary sources are limited. Here, SCCPs and MCCPs were analyzed in three categories of commonly used infant foods from the Chinese market. The mean concentrations (range) of SCCPs in infant formulas, cereals, and purees were 7.95 (2.32-54.2), 4.26 (2.73-8.81), and 4.66 (1.33-8.43) ng g fresh weight, respectively, and the mean (range) MCCP concentrations were 4.77 (1.67-20.9), 2.91 (1.21-8.24), and 1.89 (0.53-5.41) ng g fresh weight, respectively. Chlorinated paraffins (CP) concentrations in whole milk samples were significantly higher than those detected in the other infant foods (p < 0.01). This study is the first to determine the occurrence of CPs in baby purees. The estimated margin of exposure (MOE) values (SCCPs-MOE and MCCPs-MOE) in this study were all greater than 1000, indicating that there were no health risks posed by CP contamination in infant foods. Principal component analysis indicated that foods of animal origin were more influenced by MCCPs than those of plant-origin, indicating different contamination patterns of CPs between food groups.
食物摄入已被确定为婴儿摄入短链和中链氯化石蜡（SCCPs 和 MCCPs）的主要途径，但通过饮食来源评估婴儿接触 SCCPs 和 MCCPs 的情况有限。本研究分析了来自中国市场的三种常见婴儿食品中的 SCCPs 和 MCCPs。婴儿配方奶粉、谷类和泥状食品中 SCCPs 的平均浓度（范围）分别为 7.95（2.32-54.2）、4.26（2.73-8.81）和 4.66（1.33-8.43）ng/g 鲜重，MCCP 的平均浓度（范围）分别为 4.77（1.67-20.9）、2.91（1.21-8.24）和 1.89（0.53-5.41）ng/g 鲜重。全脂牛奶样本中的氯化石蜡（CP）浓度明显高于其他婴儿食品（p<0.01）。本研究首次测定了婴儿泥状食品中 CP 的含量。本研究中 SCCPs-MOE 和 MCCPs-MOE 的估计暴露边际值（MOE）均大于 1000，表明婴儿食品中 CP 污染不会对健康造成危害。主成分分析表明，动物源食品比植物源食品受 MCCPs 的影响更大，表明不同食品组之间 CP 的污染模式不同。
