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《600 例新型冠状病毒病的耳鼻喉科表现:前瞻性回顾》

Otorhinolaryngological manifestations of coronavirus disease 2019: a prospective review of 600 patients.

机构信息

Department of Laryngology (ENT), Deenanath Mangeshkar Hospital and Research Centre, Pune, India.

出版信息

J Laryngol Otol. 2021 Mar;135(3):206-211. doi: 10.1017/S0022215121000220. Epub 2021 Jan 18.

Abstract

OBJECTIVES

To evaluate otorhinolaryngological manifestations of coronavirus disease 2019 infection and the time required for their resolution.

METHODS

A prospective analysis was conducted of coronavirus disease 2019 patients presenting from 1 April 2020 to 30 July 2020. The otorhinolaryngological manifestations were evaluated based on patient history. The time required for symptom resolution was evaluated separately for intensive care unit and non-intensive care unit patients.

RESULTS

A total of 600 patients were included in the study; 13.3 per cent required the intensive care unit and 2.2 per cent expired. The otorhinolaryngological manifestations were: sore throat (88 per cent), fever (78.8 per cent), anosmia or hyposmia (63.6 per cent), ageusia or hypogeusia (63.5 per cent), rhinorrhoea (51.3 per cent), nasal obstruction (33.5 per cent), sneezing (30.3 per cent), and breathing difficulty (18.6 per cent). The time required for symptom resolution was longest for breathing difficulty (23.6 days for intensive care unit and 8.2 days for non-intensive care unit patients).

CONCLUSION

Otorhinolaryngological symptoms are one of the main presentations of coronavirus disease 2019 infection. The increased prevalence of medical co-morbidities in patients requiring intensive care unit and in deceased patients is also highlighted.

摘要

目的

评估 2019 年冠状病毒病感染的耳鼻喉科表现及其恢复所需的时间。

方法

对 2020 年 4 月 1 日至 7 月 30 日期间出现的 2019 年冠状病毒病患者进行前瞻性分析。根据患者病史评估耳鼻喉科表现。分别评估重症监护病房和非重症监护病房患者的症状缓解所需时间。

结果

共纳入 600 例患者,其中 13.3%需要重症监护病房,2.2%死亡。耳鼻喉科表现为:咽痛(88%)、发热(78.8%)、嗅觉丧失或嗅觉减退(63.6%)、味觉丧失或味觉减退(63.5%)、流涕(51.3%)、鼻塞(33.5%)、打喷嚏(30.3%)和呼吸困难(18.6%)。症状缓解所需时间最长的是呼吸困难(重症监护病房患者为 23.6 天,非重症监护病房患者为 8.2 天)。

结论

耳鼻喉科症状是 2019 年冠状病毒病感染的主要表现之一。还强调了需要重症监护病房和死亡患者中合并症患病率增加的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/480f/7925986/4ee768ecded2/S0022215121000220_fig1.jpg

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