Department of Infectious Diseases, Tosei General Hospital, Japan.
Department of Neurology, Tosei General Hospital, Japan.
Intern Med. 2021 Jun 15;60(12):1971-1976. doi: 10.2169/internalmedicine.5362-20. Epub 2021 Jan 15.
Measles encephalitis rarely affects young adults and has no established treatment strategy. This brief report described the rare case of an immunocompetent 30-year-old man with severe measles pneumonia and encephalitis, following the autoimmune disease acute disseminated encephalomyelitis, during a large measles outbreak in 2018 in Japan. With multidisciplinary treatments, including corticosteroids, intravenous immunoglobulins, vitamin A, and therapeutic plasma exchange, the patient was successfully treated. This case provides a new strategy for treating measles encephalitis and its complications during measles outbreak.
麻疹脑炎很少影响年轻成年人，且没有既定的治疗策略。本简要报告描述了一例罕见的免疫功能正常的 30 岁男性病例，他在 2018 年日本麻疹大流行期间患有严重麻疹肺炎和脑炎，继自动免疫性疾病急性播散性脑脊髓炎后发生。通过多学科治疗，包括皮质类固醇、静脉注射免疫球蛋白、维生素 A 和治疗性血浆置换，该患者成功得到治疗。该病例为麻疹流行期间麻疹脑炎及其并发症的治疗提供了新策略。
