Salk Institute For Biological Studies, Plant Molecular and Cellular Biology Laboratory, 10010 N Torrey Pines Rd, La Jolla, CA 92037, USA.
J Exp Bot. 2021 Mar 17;72(6):2154-2164. doi: 10.1093/jxb/erab012.
Iron bioavailability varies dramatically between soil types across the globe. This has given rise to high levels of natural variation in plant iron responses, allowing members of even a single species to thrive across a wide range of soil types. In recent years we have seen the use of genome-wide association analysis to identify natural variants underlying plant responses to changes in iron availability in both Arabidopsis and important crop species. These studies have provided insights into which genes have been important in shaping local adaptation to iron availability in different plant species and have allowed the discovery of novel regulators and mechanisms, not previously identified using mutagenesis approaches. Furthermore, these studies have allowed the identification of markers that can be used to accelerate breeding of future elite varieties with increased resilience to iron stress and improved nutritional quality. The studies highlighted here show that, in addition to studying plant responses to iron alone, it is important to consider these responses within the context of plant nutrition more broadly and to also consider iron regulation in relation to additional traits of agronomic importance such as yield and disease resistance.
全球不同土壤类型中铁的生物有效性差异巨大。这导致植物对铁的反应存在高度的自然变异，即使是同一物种的成员也能在广泛的土壤类型中茁壮成长。近年来，我们已经看到全基因组关联分析被用于鉴定拟南芥和重要作物物种中对铁可用性变化的植物反应的自然变异。这些研究深入了解了哪些基因在塑造不同植物物种对铁可用性的本地适应性方面发挥了重要作用，并发现了以前使用诱变方法无法识别的新的调控因子和机制。此外，这些研究还允许鉴定可以用于加速培育未来具有更高铁胁迫抗性和改善营养品质的优良品种的标记。这里强调的研究表明，除了单独研究植物对铁的反应外，重要的是要在更广泛的植物营养背景下考虑这些反应，还要考虑铁调节与其他具有农业重要性的性状（如产量和抗病性）的关系。
