Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Colon and Rectal Surgery Associates, Minneapolis, Minnesota, USA.
Neurogastroenterol Motil. 2021 Jun;33(6):e14067. doi: 10.1111/nmo.14067. Epub 2021 Jan 18.
The equipment and methods for performing anorectal manometry and biofeedback therapy are different and not standardized. Normal values are influenced by age and sex. Our aims were to generate reference values, examine effects of gender and age, and compare anorectal pressures measured with diagnostic and biofeedback catheters and a portable manometry system.
In this multicenter study, anorectal pressures at rest, during squeeze, and evacuation were measured with diagnostic and biofeedback catheters using Mcompass portable device in healthy subjects. Balloon expulsion time and rectal sensation were evaluated. The effects of age and gender were assessed.
The final dataset comprised 108 (74 women) of 124 participants with normal rectal balloon expulsion time (less than 60 s). During squeeze, anal resting pressure increased by approximately twofold in women and threefold in men. During evacuation, anal pressure exceeded rectal pressure in 87 participants (diagnostic catheter). The specific rectoanal pressures (e.g., resting pressure) were significantly correlated and not different between diagnostic and biofeedback catheters. With the diagnostic catheter, the anal squeeze pressure and rectal pressure during evacuation were greater in men than women (p ≤ 0.02). Among women, women aged 50 years and older had lower anal resting pressure; rectal pressure and the rectoanal gradient during evacuation were greater in older than younger women (p ≤ 0.01).
Anal and rectal pressures measured with diagnostic and biofeedback manometry catheters were correlated and not significantly different. Pressures were influenced by age and sex, providing reference values in men and women.
进行肛门直肠测压和生物反馈治疗的设备和方法不同且不规范。正常值受年龄和性别影响。我们的目的是生成参考值，检查性别和年龄的影响，并比较诊断和生物反馈导管以及便携式测压系统测量的肛门直肠压力。
在这项多中心研究中，使用 Mcompass 便携式设备通过诊断和生物反馈导管测量健康受试者在静息、收缩和排空期间的肛门直肠压力。评估了球囊排出时间和直肠感觉。评估了年龄和性别的影响。
最终数据集包括 124 名参与者中的 108 名（74 名女性），他们的直肠球囊排出时间正常（少于 60 秒）。在收缩期间，女性的肛门静息压力增加了大约两倍，男性增加了三倍。在排空期间，在 87 名参与者（诊断导管）中，肛门压力超过直肠压力。特定的直肠肛门压力（例如，静息压力）在诊断和生物反馈导管之间呈显著相关且无差异。使用诊断导管，男性的肛门收缩压力和排空时的直肠压力大于女性（p≤0.02）。在女性中，50 岁及以上的女性肛门静息压力较低；老年女性的直肠压力和排空时的直肠肛门梯度大于年轻女性（p≤0.01）。
使用诊断和生物反馈测压导管测量的肛门和直肠压力呈正相关且无显著差异。压力受年龄和性别影响，为男性和女性提供了参考值。
