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2020 年中国上海浦东新区针对 COVID-19 病例的主动监测措施的效果。

The effectiveness of active surveillance measures for COVID-19 cases in Pudong New Area Shanghai, China, 2020.

机构信息

Research Base of Key Laboratory of Surveillance and Early Warning of Infectious Disease of China CDC, Pudong New Area Center for Disease Control and Prevention, Shanghai, China.

Pudong Institute of Preventive Medicine, Fudan University, Shanghai, China.

出版信息

J Med Virol. 2021 May;93(5):2918-2924. doi: 10.1002/jmv.26805. Epub 2021 Feb 16.

Abstract

The aim of this study was to thoroughly document the effects of multiple intervention and control methods to mitigate the ongoing coronavirus disease 2019 (COVID-19) outbreak in Pudong New Area, Shanghai. After identification of the first confirmed case of COVID-19 in Pudong on January 21, 2020, the local Center for Disease Control and Prevention (CDC) launched a case investigation involving isolation, close-contact (CC) tracing and quarantine of persons with a potential exposure risk to prevent and control transmission. Epidemiological features of cases detected by three different strategies were compared to assess the impact of these active surveillance measures. As of February 16, 2020, a total of 108 confirmed COVID-19 cases had been identified in Pudong, Shanghai. Forty-five (41.67%) cases were identified through active surveillance measures, with 22 (20.37%) identified by CC tracing and 23 (21.30%) by quarantine of potential exposure populations (PEPs). The average interval from illness onset to the first medical visit was 1 day. Cases identified by CC tracing and PEPs were quarantined for 0.5 and 1 day before illness onset, respectively. The time intervals from illness onset to the first medical visit and isolation among actively screened cases were 2 days (p = .02) and 3 days (p = .00) shorter, respectively, than those among self-admission cases. Our study highlights the importance of active surveillance for potential COVID-19 cases, as demonstrated by shortened time intervals from illness onset to both the first medical visit and isolation. These measures contributed to the effective control of the COVID-19 outbreak in Pudong, Shanghai.

摘要

本研究旨在全面记录多种干预和控制措施对减轻上海浦东新区 2019 年冠状病毒病(COVID-19)疫情的影响。2020 年 1 月 21 日确认浦东新区首例 COVID-19 病例后,当地疾病预防控制中心(CDC)启动了病例调查,包括隔离、密切接触者(CC)追踪和对有潜在暴露风险的人员进行检疫,以预防和控制传播。比较了通过三种不同策略检测到的病例的流行病学特征,以评估这些主动监测措施的效果。截至 2020 年 2 月 16 日,上海浦东新区共确诊 108 例 COVID-19 病例。45 例(41.67%)通过主动监测措施发现,其中 22 例(20.37%)通过 CC 追踪发现,23 例(21.30%)通过隔离潜在接触人群(PEPs)发现。从发病到首次就诊的平均间隔为 1 天。通过 CC 追踪和 PEP 发现的病例在发病前分别隔离 0.5 和 1 天。主动筛查病例从发病到首次就诊和隔离的时间间隔分别缩短了 2 天(p=0.02)和 3 天(p=0.00),而自行就医的病例的间隔时间分别缩短了 2 天(p=0.02)和 3 天(p=0.00)。我们的研究强调了对潜在 COVID-19 病例进行主动监测的重要性,因为从发病到首次就诊和隔离的时间间隔均缩短。这些措施有助于有效控制上海浦东新区的 COVID-19 疫情。

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