Key Laboratory of Plant Secondary Metabolism and Regulation of Zhejiang Province, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Key Laboratory of Plant Secondary Metabolism and Regulation of Zhejiang Province, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
J Ethnopharmacol. 2021 May 10;271:113836. doi: 10.1016/j.jep.2021.113836. Epub 2021 Jan 16.
Tetrastigma hemsleyanum Diels et Gilg, known as Sanyeqing in China, was an extensively used folk Chinese herbal medicine. This plant had been validated to be highly effective for treating high fever, pneumonia, hepatitis, gastritis, cervicitis, lymphatic tuberculosis, septicemia, and viral meningitis.
As a review in T. hemsleyanum, this article aims to provide a critical and comprehensive evaluation for future research as well as the development of new drugs. The possible uses and future research directions of this plant were also discussed.
A literature search was conducted on different scientific search engines, including Google Scholar, Science Direct, PubMed, Web of Science, and CNKI. Additional information was obtained from classic books about Chinese herbal medicine and scientific databases.
T. hemsleyanum was a perennial herb climbing vine, which was mainly based on field cultivation. About 150 chemical compounds have been isolated from T. hemsleyanum, including flavonoids, phenolic acids, polysaccharides, triterpenoids, steroids, and organic acids. Studies on the physiological aspects of T. hemsleyanum have been focused on the effects of light and fertilizer on their growth, and few other studies have been conducted. The plant had widespread pharmacological effects on the immune system, as well as anti-tumor, anti-inflammatory, analgesic, and antipyretic.
T. hemsleyanum was a valuable traditional Chinese medical herb with pharmacological activities that mainly affected the immune system. This review summarized its botanical description, cultivation techniques, physiology, ethnopharmacology, chemical components, and pharmacological functions. This information suggested that we should focus on the development of new drugs related to T. hemsleyanum. Meanwhile, it was important to emphasize the traditional use of T. hemsleyanum, avoiding over-harvesting that exerted a great impact on resource scarcity. And developing its new clinical usage and comprehensive utilize would augment the therapeutic potentials of T. hemsleyanum.
中国民间草药三叶藤 Tetrastigma hemsleyanum Diels et Gilg，俗称三叶青，已被证明对治疗高热、肺炎、肝炎、胃炎、宫颈炎、淋巴结核、败血症和病毒性脑膜炎具有高度疗效。
作为对三叶藤的综述，本文旨在为未来的研究和新药开发提供批判性和全面的评估。还讨论了该植物的可能用途和未来研究方向。
在不同的科学搜索引擎上进行了文献检索，包括 Google Scholar、Science Direct、PubMed、Web of Science 和中国知网。还从中药经典著作和科学数据库中获取了其他信息。
三叶藤是一种多年生藤本攀援植物，主要基于田间栽培。从三叶藤中分离得到约 150 种化合物，包括黄酮类、酚酸类、多糖类、三萜类、甾体类和有机酸类。对三叶藤生理方面的研究主要集中在光照和肥料对其生长的影响上，其他方面的研究较少。该植物对免疫系统具有广泛的药理作用，同时具有抗肿瘤、抗炎、镇痛和退热作用。
三叶藤是一种具有药理活性的有价值的传统中药，主要影响免疫系统。本综述总结了其植物学描述、栽培技术、生理学、民族药理学、化学成分和药理学功能。这些信息表明，我们应该专注于开发与三叶藤相关的新药。同时，强调三叶藤的传统用途，避免过度采集对资源稀缺造成的巨大影响。开发其新的临床用途和综合利用将增加三叶藤的治疗潜力。
