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从一只患病的家养宠物猫身上分离出的具有人畜共患潜力的人类病原(原 I 型),日本。

Human pathogenic (former subtype I) with zoonotic potential isolated from a diseased indoor pet cat, Japan.

机构信息

Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.

Terazono Animal Clinic, Hiroshima, Japan.

出版信息

Emerg Microbes Infect. 2021 Dec;10(1):220-222. doi: 10.1080/22221751.2021.1878935.

DOI:10.1080/22221751.2021.1878935
PMID:33467980
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7872583/
Abstract

Nontuberculous mycobacterial (NTM) infections in humans have increased in prevalence in recent decades. is one of the most prevalent human pathogenic NTM species worldwide Herein, we report the first isolation of from an indoor domestic cat in Japan. Comparative genome sequence analysis of the feline isolate showed this pathogen is genetically identical to human pathogenic . This finding suggests that has a potential risk of zoonoses and requires the "One Health" approach to control NTM infection.

摘要

近年来,人类中非结核分枝杆菌(NTM)感染的患病率呈上升趋势。 是世界范围内最普遍的人类致病性 NTM 物种之一。在此,我们报告了首例从日本室内家猫中分离出 的病例。对该猫源分离株的比较基因组序列分析表明,该病原体与人类致病性 完全相同。这一发现表明 具有潜在的人畜共患病风险,需要采用“同一健康”方法来控制 NTM 感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5860/7872583/bbc3310c0ad8/TEMI_A_1878935_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5860/7872583/bbc3310c0ad8/TEMI_A_1878935_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5860/7872583/bbc3310c0ad8/TEMI_A_1878935_F0001_OC.jpg

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Front Cell Infect Microbiol. 2020 Mar 24;10:122. doi: 10.3389/fcimb.2020.00122. eCollection 2020.
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Genomic Insights Into the Complex: An Update.关于该复合体的基因组学见解:最新进展
Animals (Basel). 2022 Apr 8;12(8):964. doi: 10.3390/ani12080964.
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