Tamukai Kenichi, Minami Shohei, Kadekaru Sho, Mitsui Ikki, Maeda Ken, Une Yumi
Den-en-chofu Animal Hospital, 2-1-3 Denenchofu, Ota-ku, Tokyo 145-0071, Japan.
Laboratory of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida-shi, Yamaguchi 753-8515, Japan.
J Vet Med Sci. 2021 Apr 3;83(3):507-511. doi: 10.1292/jvms.20-0480. Epub 2021 Jan 21.
Post-import from the Republic of Indonesia to Japan in 2017, two juvenile, captive bred Asian small-clawed otters (Aonyx cinereus) exhibited gastrointestinal symptoms, including vomiting, diarrhea, and hematemesis, and died. One of them was examined postmortem. Microscopically, the small intestinal mucosa was necrotic with crypts lined by regenerating large epithelial cells. A gastric cardiac mucosal ulcerative lesion containing fungal yeasts and pseudohyphae morphologically indicated Candida spp. The lymph nodes exhibited marked lymphoid depletion. Canine parvovirus 2 (CPV-2) was isolated from an oral swab, and virus protein 2 (VP2) gene sequencing revealed new CPV-2a. To our knowledge, this is the first new CPV-2a infection report in Asian small-clawed otters. This infection should be considered in gastrointestinal symptom-related cases in this species.
2017年从印度尼西亚共和国进口到日本后，两只人工饲养的幼年亚洲小爪水獭（Aonyx cinereus）出现了胃肠道症状，包括呕吐、腹泻和吐血，随后死亡。其中一只在死后进行了检查。显微镜下，小肠黏膜坏死，隐窝由再生的大上皮细胞排列。胃贲门黏膜溃疡性病变含有真菌酵母和假菌丝，形态学上表明为念珠菌属。淋巴结显示出明显的淋巴细胞耗竭。从口腔拭子中分离出犬细小病毒2型（CPV-2），病毒蛋白2（VP2）基因测序显示为新的CPV-2a。据我们所知，这是亚洲小爪水獭中首次出现新的CPV-2a感染报告。在该物种出现胃肠道症状相关病例时应考虑这种感染。
