Schoustra Sjoukje M, Op 't Root Tim J P M, Pompe van Meerdervoort Rutger P, Alink Laurens, Steenbergen Wiendelt, Manohar Srirang
Multi-Modality Medical Imaging Group, Technical Medical Centre, University of Twente, P.O. Box 217, 7500 AE, Enschede, the Netherlands.
Biomedical Photonic Imaging Group, Technical Medical Centre, University of Twente, P.O. Box 217, 7500 AE, Enschede, the Netherlands.
Photoacoustics. 2020 Dec 26;21:100238. doi: 10.1016/j.pacs.2020.100238. eCollection 2021 Mar.
This work describes the design, development and added value of breast-supporting cups to immobilize and position the pendant breast in photoacoustic tomographic imaging. We explain the considerations behind the choice of the material, the shape and sizes of a cup-shaped construct for supporting the breast in water in an imaging tank during full-breast imaging. We provide details of the fabrication, and other processing and testing procedures used. Various experiments were conducted to demonstrate the added value of using these cups. We show that breast movement during a measurement time of four minutes is reduced from maximum 2 mm to 0.1 mm by the use of cups. Further, the presence of the cup, centered in the aperture leading to the imaging tank, ensures that the breast can be reproducibly positioned at the center of the field-of-view of the detection aperture in the tank. Finally, since an accurate delineation of the water-tissue boundary can now be made, the use of the cup enables accurate application of a two-speed of sound model for reconstruction. All in all, we demonstrate that the use of cups to support the breast provides clear enhancement in contrast and resolution of breast images in photoacoustic imaging.
这项工作描述了用于在光声断层成像中固定和定位下垂乳房的支撑杯的设计、开发及附加价值。我们解释了在全乳成像期间，为在成像水槽的水中支撑乳房而选择杯状结构的材料、形状和尺寸背后的考量因素。我们提供了制造以及所使用的其他加工和测试程序的详细信息。进行了各种实验以证明使用这些支撑杯的附加价值。我们表明，通过使用支撑杯，在四分钟的测量时间内乳房运动从最大2毫米减少到了0.1毫米。此外，位于通向成像水槽的孔径中心的支撑杯确保了乳房能够可重复地定位在水槽中检测孔径视场的中心。最后，由于现在可以精确描绘水 - 组织边界，支撑杯的使用使得能够准确应用双声速模型进行重建。总而言之，我们证明了使用支撑杯支撑乳房在光声成像中能显著提高乳房图像的对比度和分辨率。
