基于钆的造影剂的磁共振测温法。
Magnetic resonance thermometry using a Gd-based contrast agent.
机构信息
Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, USA.
出版信息
Chem Commun (Camb). 2021 Feb 18;57(14):1770-1773. doi: 10.1039/d0cc06400a. Epub 2021 Jan 21.
Abstract
The complexes described here serve as contrast agents for magnetic resonance imaging thermometry. The complexes differentially enhance contrast between 275 and 325 K. The basis of the temperature response of the fluorinated contrast complex is the modulation of water exchange caused by trifluoromethyl groups that can be chemically controlled.
摘要
这里描述的配合物可用作磁共振成像测温的对比剂。这些配合物在 275 和 325 K 之间可产生差异增强对比。氟化对比配合物的温度响应的基础是三氟甲基基团引起的水交换的调制，该调制可以通过化学控制。
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