Data Science Research Program, American Cancer Society, Atlanta, GA, United States.
Data Science Research Program, American Cancer Society, Atlanta, GA, United States; School of Public Health, University of Illinois at Chicago, Chicago, IL, United States.
Cancer Epidemiol. 2021 Apr;71(Pt A):101893. doi: 10.1016/j.canep.2021.101893. Epub 2021 Jan 19.
Alcohol consumption is an established risk factor for several cancer types, but there are no contemporary published estimates of the state-level burden of cancer attributed to alcoholic beverage consumption. Such estimates are needed to inform public policy and cancer control efforts. We estimated the proportion and number of incident cancer cases and cancer deaths attributable to alcohol consumption by sex in adults aged ≥30 years in all 50 states and the District of Columbia in 2013-2016.
Age-, sex-, and state-specific cancer incidence and mortality data (2013-2016) were obtained from the US Cancer Statistics database. State-level, self-reported age and sex stratified alcohol consumption prevalence was estimated using the 2003-2006 Behavioral Risk Factor Surveillance System surveys and adjusted with state sales data.
The proportion of alcohol-attributable incident cancer cases ranged from 2.9 % (95 % confidence interval: 2.7 %-3.1 %) in Utah to 6.7 % (6.4 %-7.0 %) in Delaware among men and women combined, from 2.7 % (2.5 %-3.0 %) in Utah to 6.3 % (5.9 %-6.7 %) in Hawaii among men, and from 2.7 % (2.4 %-3.0 %) in Utah to 7.7 % (7.2 %-8.3 %) in Delaware among women. The proportion of alcohol-attributable cancer deaths also varied considerably across states: from 1.9 % to 4.5 % among men and women combined, from 2.1% to 5.0% among men, and from 1.4 % to 4.4 % among women. Nationally, alcohol consumption accounted for 75,199 cancer cases and 18,947 cancer deaths annually.
Alcohol consumption accounts for a considerable proportion of cancer incidence and mortality in all states. Implementing state-level policies and cancer control efforts to reduce alcohol consumption could reduce this cancer burden.
饮酒是多种癌症类型的既定风险因素，但目前尚无关于 2013-2016 年全美 50 个州和哥伦比亚特区因饮用酒精饮料导致癌症负担的州级数据。这些数据对于制定公共政策和癌症防控措施非常必要。我们估算了 2013-2016 年所有年龄≥30 岁的成年人中因饮酒导致的癌症发病和死亡病例数及比例。
我们从美国癌症统计数据库获取了年龄、性别和州特异性癌症发病率和死亡率数据（2013-2016 年）。我们利用 2003-2006 年行为风险因素监测系统调查，结合各州销售数据，估计了州级、按年龄和性别分层的饮酒流行率，并进行了调整。
男性和女性合计的酒精归因癌症发病比例，从犹他州的 2.9%（95%置信区间：2.7%-3.1%）到特拉华州的 6.7%（6.4%-7.0%），男性从犹他州的 2.7%（2.5%-3.0%）到夏威夷州的 6.3%（5.9%-6.7%），女性从犹他州的 2.7%（2.4%-3.0%）到特拉华州的 7.7%（7.2%-8.3%）。各州的酒精归因癌症死亡比例也存在较大差异：男性和女性合计为 1.9%-4.5%，男性为 2.1%-5.0%，女性为 1.4%-4.4%。全国范围内，酒精消费导致每年 75199 例癌症发病和 18947 例癌症死亡。
在所有州，酒精消费都导致了相当比例的癌症发病和死亡。实施州级政策和癌症防控措施减少酒精消费，可能会降低这一癌症负担。
