Dima Alina, Balaban Daniel Vasile, Jurcut Ciprian, Berza Ioana, Jurcut Ruxandra, Jinga Mariana
Colentina Clinical Hospital, 072202 Bucharest, Romania.
Internal Medicine and Gastroenterology Clinic, Carol Davila University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Healthcare (Basel). 2021 Jan 18;9(1):95. doi: 10.3390/healthcare9010095.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) was declared a pandemic in March 2020, triggering important changes for the entire society and healthcare systems, as well as significant lockdown measures aimed to limit the disease spread. We herein intended to catch the dynamic of Romanian physicians' perceptions of COVID-19 impact. For this purpose, after a literature review, a 30-item questionnaire was designed. The questionnaire was twice distributed online, about 1 month apart, during which partial relaxation measures were decreed in Romania. The questionnaire was voluntarily filled in by Romanian physicians who were willing to participate in the study. A total of 214 physicians answered the questionnaire upon its first release, and 199 respondents were registered upon its second release, most of whom (94.9%) were involved in clinical work, with one-third working in units dedicated to COVID-19 patients. In parallel with the relaxation of lockdown measures, along with increased confidence in the efficiency of protective measures (46.7% vs. 31.3%), separation from household members decreased from 36.9% to 22.1%. Nevertheless, the feeling of rejection felt by doctors remained similar (22.4% vs. 24.6%). Furthermore, answers regarding the clinical picture, diagnostic approach, and treatment options are discussed. Most of therapeutic options considered for SARS-CoV-2 treatment (e.g., lopinavir/ritonavir, oseltamivir, hydroxychloroquine, azithromycin, tocilizumab, and convalescent plasma) failed to confirm significant efficiency. On the contrary, vaccines for widescale use are already available despite the initial skepticism. In the beginning of the pandemic, 25.2% (18.2% vs. 32.2%) considered that there will not be an effective COVID-19 vaccine, while 41.6% (43.0% vs. 40.2%) thought that a vaccine would be available after at least 12 months. In conclusion, initially, following only a 1 month period, Romanian physicians' intention to consider treatments such as hydroxychloroquine or lopinavir/ritonavir for COVID-19 decreased significantly. Moreover, confidence in the efficiency of available protective measures increased, and the rates of separation from household members decreased.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）疾病（COVID-19）于2020年3月被宣布为大流行病，给整个社会和医疗系统带来了重大变化，同时也实施了旨在限制疾病传播的重大封锁措施。我们在此旨在了解罗马尼亚医生对COVID-19影响的看法动态。为此，在进行文献综述后，设计了一份包含30个条目的问卷。该问卷在网上分两次发放，间隔约1个月，在此期间罗马尼亚颁布了部分放宽措施。问卷由愿意参与研究的罗马尼亚医生自愿填写。问卷首次发放时有214名医生回答，第二次发放时有199名受访者登记，其中大多数（94.9%）从事临床工作，三分之一在专门收治COVID-19患者的科室工作。随着封锁措施的放宽，对防护措施有效性的信心增强（46.7%对31.3%），与家庭成员分开的比例从36.9%降至22.1%。然而，医生所感受到的被排斥感仍相似（22.4%对24.6%）。此外，还讨论了关于临床表现、诊断方法和治疗选择的答案。大多数用于SARS-CoV-2治疗的选择（如洛匹那韦/利托那韦、奥司他韦、羟氯喹、阿奇霉素、托珠单抗和康复期血浆）未能证实具有显著疗效。相反，尽管最初存在怀疑，但大规模使用的疫苗已经问世。在疫情初期，25.2%（18.2%对32.2%）的人认为不会有有效的COVID-19疫苗，而41.6%（43.0%对40.2%）的人认为至少12个月后才会有疫苗。总之，最初，仅在1个月后，罗马尼亚医生考虑将羟氯喹或洛匹那韦/利托那韦等用于COVID-19治疗的意愿就显著下降。此外，对现有防护措施有效性的信心增强，与家庭成员分开的比例降低。
