University of Medicine and Pharmacy "Carol Davila", 37 Dionisie Lupu Str., 020021, Bucharest, Romania.
National Institute of Diabetes, Nutrition and Metabolic Diseases "N. C. Paulescu", 5-7. Ion Movila Str, 030167, Bucharest, Romania.
Sci Rep. 2020 Dec 10;10(1):21613. doi: 10.1038/s41598-020-78575-w.
Evidence regarding the relation between SARS-CoV-2 mortality and the underlying medical condition is scarce. We conducted an observational, retrospective study based on Romanian official data about location, age, gender and comorbidities for COVID-19 fatalities. Our findings indicate that males, hypertension, diabetes, obesity and chronic kidney disease were most frequent in the COVID-19 fatalities, that the burden of disease was low, and that the prognosis for 1-year survival probability was high in the sample. Evidence shows that age-dependent pairs of comorbidities could be a negative prognosis factor for the severity of disease for the SARS-CoV 2 infection.
关于 SARS-CoV-2 死亡率与基础疾病之间关系的证据很少。我们基于罗马尼亚关于 COVID-19 死亡病例的位置、年龄、性别和合并症的官方数据，进行了一项观察性、回顾性研究。我们的研究结果表明，男性、高血压、糖尿病、肥胖和慢性肾脏病在 COVID-19 死亡病例中最为常见，疾病负担较低，样本中 1 年生存率的预后较高。有证据表明，年龄相关的合并症对 SARS-CoV-2 感染的疾病严重程度可能是一个负面预后因素。
