从植物内生真菌中分离得到的一些新次生代谢产物的生物活性：综述研究。
Biological Activities of Some New Secondary Metabolites Isolated from Endophytic Fungi: A Review Study.
机构信息
Gene Engineering and Biotechnology Beijing Key Laboratory, College of Life Science, Beijing Normal University, 19 XinjiekouWai Avenue, Beijing 100875, China.
出版信息
Int J Mol Sci. 2021 Jan 19;22(2):959. doi: 10.3390/ijms22020959.
Secondary metabolites isolated from plant endophytic fungi have been getting more and more attention. Some secondary metabolites exhibit high biological activities, hence, they have potential to be used for promising lead compounds in drug discovery. In this review, a total of 134 journal articles (from 2017 to 2019) were reviewed and the chemical structures of 449 new metabolites, including polyketides, terpenoids, steroids and so on, were summarized. Besides, various biological activities and structure-activity relationship of some compounds were aslo described.
从植物内生真菌中分离得到的次生代谢产物越来越受到关注。一些次生代谢产物表现出很高的生物活性，因此它们有可能被用于发现有前途的药物先导化合物。在本综述中，共综述了 134 篇期刊文章（2017-2019 年），总结了 449 种新代谢产物的化学结构，包括聚酮类、萜类、甾体等。此外，还描述了一些化合物的各种生物活性和构效关系。
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