Flint A, Kumar N B, Naylor B
Department of Pathology, University of Michigan Medical Center, Ann Arbor 48109-0054.
Acta Cytol. 1988 Mar-Apr;32(2):221-5.
The cytologic manifestations of pulmonary Hodgkin's disease in transthoracic fine needle aspirates from 13 patients with pulmonary radiologic abnormalities and a previous diagnosis of Hodgkin's disease are described. Classic Reed-Sternberg cells and lacunar cells were present in most cases. The so-called "mononuclear" Reed-Sternberg cells were identified in all cases. A cellular background consisting of variable numbers of histiocytes, eosinophilic and neutrophilic leukocytes and lymphocytes was frequently present. Such a background should stimulate a search for cells diagnostic of Hodgkin's disease. We conclude that the cytologic features of Hodgkin's disease are not only characteristic, but are also diagnostic, in patients with a prior history of Hodgkin's disease in whom pulmonary recurrence is suspected.
本文描述了13例肺部有放射学异常且先前已诊断为霍奇金病患者经胸细针穿刺抽吸物中肺部霍奇金病的细胞学表现。大多数病例中存在典型的里德-斯腾伯格细胞和陷窝细胞。所有病例均识别出所谓的“单核”里德-斯腾伯格细胞。经常可见由数量不等的组织细胞、嗜酸性和嗜中性白细胞及淋巴细胞组成的细胞背景。这样的背景应促使寻找诊断霍奇金病的细胞。我们得出结论，对于怀疑有肺部复发且有霍奇金病既往史的患者，霍奇金病的细胞学特征不仅具有特征性，而且具有诊断性。
