Pediatric Department, National Hospital Edgardo Rebagliati Martins, Lima, Peru.
Critical Pediatrics Department, Instituto Nacional de Salud del Niño, Lima, Peru.
BMJ Case Rep. 2022 May 20;15(5):e248478. doi: 10.1136/bcr-2021-248478.
New diagnoses of leukaemia and other malignancies are recently being made in paediatric patients with COVID-19. The rates of mortality and morbidity in some of these children are expected to be higher. In new cases, concurrent diagnosis can be difficult because multisystemic inflammatory syndrome (MIS-C) and malignancies have similar clinical presentations. We present the case of a preteenage child where the diagnosis of leukaemia was complicated and delayed by a multisystem involvement and an inconclusive bone marrow study. Clinical teams managing children with COVID-19 and MIS-C should suspect leukaemia and other malignancies when the clinical course is complicated and bone marrow suppression is persistent. Prompt diagnosis will allow start of treatment on time, minimising complications.
近期，COVID-19 患儿中出现了新的白血病和其他恶性肿瘤的诊断。这些儿童的死亡率和发病率预计会更高。在新病例中，由于儿童多系统炎症综合征（MIS-C）和恶性肿瘤具有相似的临床表现，同时诊断可能具有挑战性。我们报告了一例青少年患者的病例，其白血病的诊断因多系统受累和骨髓研究结果不确定而变得复杂和延迟。管理 COVID-19 和 MIS-C 患儿的临床团队在病程复杂且骨髓抑制持续存在时，应怀疑白血病和其他恶性肿瘤。及时诊断将使治疗能够及时开始，从而最大程度地减少并发症。
