Wen Jialin, Wang Fangyuan, Zhang Xumu
Department of Chemistry, Guangdong Provincial Key Laboratory of Catalysis, Southern University of Science and Technology, 1088 Xueyuan Road, Shenzhen, 518055, China.
Chem Soc Rev. 2021 Mar 7;50(5):3211-3237. doi: 10.1039/d0cs00082e. Epub 2021 Jan 22.
This review provides a comprehensive view of the application of first-row transition metals in asymmetric hydrogenation and asymmetric transfer hydrogenation. The catalytic behavior of 3d metals is significantly different from that of 4d and 5d metals. The replacement of noble metals with first-row transition metals has encountered challenges such as different reaction mechanisms and unexpected deactivation of the catalyst. The potential involvement of a single-electron process has been the most notorious feature of first-row metals. This review aims to give readers a picture of how first-row transition metals catalyze hydrogenation reactions and the corresponding enantioinduction models. Although this article is partitioned according to the substrate type, it is mechanism-oriented and is focused on catalytic systems. A certain catalytic system could be applied in the hydrogenation of different types of double bonds. Similarities within first-row metals and differences from their 4d and 5d congeners were emphasized.
本综述全面介绍了第一行过渡金属在不对称氢化和不对称转移氢化中的应用。3d金属的催化行为与4d和5d金属有显著不同。用第一行过渡金属替代贵金属面临着不同反应机理和催化剂意外失活等挑战。单电子过程的潜在参与一直是第一行金属最显著的特征。本综述旨在让读者了解第一行过渡金属如何催化氢化反应以及相应的对映体诱导模型。尽管本文是根据底物类型划分的，但它以机理为导向，重点关注催化体系。某一催化体系可应用于不同类型双键的氢化反应。文中强调了第一行金属之间的相似性以及它们与4d和5d同族元素的差异。
