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本文引用的文献

1
Predicting Autism in Infancy.预测婴儿期自闭症
J Am Acad Child Adolesc Psychiatry. 2021 Aug;60(8):958-967. doi: 10.1016/j.jaac.2020.07.910. Epub 2020 Nov 5.
2
Factors associated with enrollment into a clinical trial of caregiver-implemented intervention for infants at risk for autism spectrum disorder.与纳入针对自闭症谱系障碍风险婴儿的照顾者实施干预临床试验相关的因素。
Autism. 2020 Oct;24(7):1874-1884. doi: 10.1177/1362361320928829. Epub 2020 Jun 29.
3
"If He Has it, We Know What to Do": Parent Perspectives on Familial Risk for Autism Spectrum Disorder.“如果他有,我们知道该怎么做”:父母对自闭症谱系障碍家族风险的看法。
J Pediatr Psychol. 2020 Mar 1;45(2):121-130. doi: 10.1093/jpepsy/jsz076.
4
Time-Lag Between Diagnosis of Autism Spectrum Disorder and Onset of Publicly-Funded Early Intensive Behavioral Intervention: Do Race-Ethnicity and Neighborhood Matter?自闭症谱系障碍诊断与公共资助早期强化行为干预开始之间的时间滞后:种族和族裔以及邻里关系重要吗?
J Autism Dev Disord. 2018 Feb;48(2):561-571. doi: 10.1007/s10803-017-3354-3.
5
Functional neuroimaging of high-risk 6-month-old infants predicts a diagnosis of autism at 24 months of age.对6个月大高危婴儿进行的功能性神经成像可预测其在24个月大时是否会被诊断为自闭症。
Sci Transl Med. 2017 Jun 7;9(393). doi: 10.1126/scitranslmed.aag2882.
6
Personal utility in genomic testing: a systematic literature review.基因检测中的个人效用:一项系统的文献综述
Eur J Hum Genet. 2017 Jun;25(6):662-668. doi: 10.1038/ejhg.2017.10. Epub 2017 Mar 15.
7
To Screen or Not to Screen Universally for Autism is not the Question: Why the Task Force Got It Wrong.普遍筛查自闭症与否并非问题所在:为何特别工作组搞错了。
J Pediatr. 2016 Sep;176:182-94. doi: 10.1016/j.jpeds.2016.06.004. Epub 2016 Jul 12.
8
The psychological impact of genetic information on children: a systematic review.基因信息对儿童的心理影响:一项系统综述。
Genet Med. 2016 Aug;18(8):755-62. doi: 10.1038/gim.2015.181. Epub 2016 Jan 7.
9
Points to Consider: Ethical, Legal, and Psychosocial Implications of Genetic Testing in Children and Adolescents.需考虑的要点:儿童和青少年基因检测的伦理、法律及社会心理影响
Am J Hum Genet. 2015 Jul 2;97(1):6-21. doi: 10.1016/j.ajhg.2015.05.022.
10
Ethical, Legal, and Clinical Considerations when Disclosing a High-Risk Syndrome for Psychosis.披露精神病高风险综合征时的伦理、法律和临床考量
Bioethics. 2015 Oct;29(8):543-56. doi: 10.1111/bioe.12155. Epub 2015 Feb 17.

婴儿自闭症谱系障碍预测的伦理问题。

The Ethics of Predicting Autism Spectrum Disorder in Infancy.

机构信息

University of Washington, Seattle; Treuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Washington.

University of Washington, Seattle.

出版信息

J Am Acad Child Adolesc Psychiatry. 2021 Aug;60(8):942-945. doi: 10.1016/j.jaac.2021.01.006. Epub 2021 Jan 19.

DOI:10.1016/j.jaac.2021.01.006
PMID:33482291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8629367/
Abstract

Toward the end of a routine check-in appointment with your young patient-a 3-year-old boy recently diagnosed with autism spectrum disorder (ASD)-his mother shares concerns about his infant sister, currently 6 months old. The mother is aware that her daughter is at increased risk for ASD. She requests a magnetic resonance imaging (MRI) scan of her infant's brain, based on research she has read showing that MRI can be used to predict which infants will go on to develop ASD. The mother communicates that she is eager to know whether her daughter is going to develop autism so that she and her husband can prepare financially, and so she can place her daughter on the long waitlist for autism-specific services in her local community. As this family's psychiatrist, how should you respond to her request?

摘要

在与你年幼的患者(一名最近被诊断出患有自闭症谱系障碍的 3 岁男孩)的常规就诊接近尾声时,他的母亲表达了对其 6 个月大的婴儿妹妹的担忧。母亲知道她的女儿患自闭症谱系障碍的风险增加。她根据自己读到的研究请求对她女儿的大脑进行磁共振成像(MRI)扫描,该研究表明 MRI 可用于预测哪些婴儿将发展为自闭症谱系障碍。母亲表示,她渴望知道女儿是否会患上自闭症,以便她和她的丈夫可以为此做好经济上的准备,这样她就可以为女儿在当地社区的自闭症特定服务中排上长队。作为这个家庭的精神科医生,你应该如何回应她的请求?