Arduino Alessandro, Zanovello Umberto, Hand Jeff, Zilberti Luca, Brühl Rüdiger, Chiampi Mario, Bottauscio Oriano
Istituto Nazionale di Ricerca Metrologica (INRIM), Torino, Italy.
School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Magn Reson Med. 2021 Jun;85(6):3447-3462. doi: 10.1002/mrm.28666. Epub 2021 Jan 22.
To investigate how the simultaneous exposure to gradient and RF fields affects the temperature rise in patients with a metallic hip prosthesis during an MRI session.
In silico analysis was performed with an anatomically realistic human model with CoCrMo hip implant in 12 imaging positions. The analysis was performed at 1.5 T and 3 T, considering four clinical sequences: turbo spin-echo, EPI, gradient-echo, and true fast imaging sequence with steady precession. The exposure to gradient and RF fields was evaluated separately and superposed, by adopting an ad hoc computational algorithm. Temperature increase within the body, rather than specific absorption rate, was used as a safety metric.
With the exception of gradient-echo, all investigated sequences produced temperature increases higher than 1 K after 360 seconds, at least for one body position. In general, RF-induced heating dominates the turbo spin-echo sequence, whereas gradient-induced heating prevails with EPI; the situation with fast imaging sequence with steady precession is more diversified. The RF effects are enhanced when the implant is within the RF coil, whereas the effects of gradient fields are maximized if the prosthesis is outside the imaging region. Cases for which temperature-increase thresholds were exceeded were identified, together with the corresponding amount of tissue mass involved and the exposure time needed to reach these limits.
The analysis confirms that risky situations may occur when a patient carrying a hip implant undergoes an MRI exam and that, in some cases, the gradient field heating may be significant. In general, exclusion criteria only based on whole-body specific absorption rate may not be sufficient to ensure patients' safety.
研究在磁共振成像(MRI)检查过程中,梯度场和射频(RF)场同时作用对金属髋关节假体患者体温升高的影响。
使用包含钴铬钼髋关节植入物的解剖学真实人体模型,在12个成像位置进行计算机模拟分析。分析在1.5T和3T场强下进行,考虑四种临床序列:快速自旋回波、回波平面成像(EPI)、梯度回波以及稳态进动快速成像序列。通过采用专门的计算算法,分别评估并叠加梯度场和RF场的暴露情况。将体内温度升高而非比吸收率用作安全指标。
除梯度回波序列外,所有研究序列在360秒后至少在一个身体位置产生的体温升高超过1K。一般来说,RF诱导加热在快速自旋回波序列中占主导,而梯度诱导加热在EPI序列中占优势;稳态进动快速成像序列的情况则更为多样。当植入物位于RF线圈内时,RF效应增强,而当假体位于成像区域外时,梯度场效应最大。确定了超过体温升高阈值的情况,以及相应涉及的组织质量和达到这些极限所需的暴露时间。
分析证实,携带髋关节植入物的患者进行MRI检查时可能会出现危险情况,并且在某些情况下,梯度场加热可能很显著。一般而言,仅基于全身比吸收率的排除标准可能不足以确保患者安全。