Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
Gastroenterology and Hepatology Unit, Department of Internal Medicine and Medical Specialties "PROMISE", University of Palermo, Palermo, Italy.
Liver Int. 2021 Apr;41(4):649-655. doi: 10.1111/liv.14796. Epub 2021 Feb 8.
The World Health Organization (WHO) targets for eliminating HCV by 2030 may be overambitious for many high-income countries. Recent analyses (ie, data from 2017 to 2019) show that only 11 countries are on track for meeting WHO's elimination targets. For a country to be truly on track, it is important that the majority of infected individuals be identified and treated. There is still a need for country and population-specific evaluations within the different HCV screening and treatment strategies available, in order to assess their cost-effectiveness and sustainability and support an evidence-based policy for HCV elimination. Any health policy model is affected by the diversity and quality of the available data and by gaps in data. Given the differences among countries, comparing progress based on fixed global targets will not necessarily be suitable in the same measure for each country. In a recent document, the European Collaborators of Polaris Observatory provide insight into the limitations of the current WHO targets. The absolute targets identified by each country in accordance with the measures set by WHO would be essential in reaching the HCV elimination. All analytic models to assess the progress towards HCV elimination are based on projections to 2030 not including the impact of the COVID-19 pandemic on hepatitis-related services. With specific regard to the achievement of WHO hepatitis elimination goals, all measures that will be put in place during and after COVID-19 pandemic could be transferred in increasing diagnosis and linkage to care of people with hepatitis.
世界卫生组织（WHO）到 2030 年消除 HCV 的目标对于许多高收入国家来说可能过于雄心勃勃。最近的分析（即 2017 年至 2019 年的数据）表明，只有 11 个国家有望实现世卫组织的消除目标。为了使一个国家真正走上正轨，重要的是要发现并治疗大多数受感染的个体。在不同的 HCV 筛查和治疗策略中，仍然需要对每个国家和人群进行具体的评估，以评估其成本效益和可持续性，并为 HCV 消除提供基于证据的政策支持。任何卫生政策模式都受到可用数据的多样性和质量以及数据差距的影响。鉴于各国之间的差异，基于固定的全球目标来比较进展情况不一定适合每个国家。在最近的一份文件中，欧洲 Polaris 观测站的合作者深入探讨了当前世卫组织目标的局限性。根据世卫组织设定的措施，每个国家确定的绝对目标对于实现 HCV 消除至关重要。所有用于评估 HCV 消除进展的分析模型都是基于到 2030 年的预测，不包括 COVID-19 大流行对肝炎相关服务的影响。具体来说，为了实现世卫组织消除肝炎的目标，在 COVID-19 大流行期间和之后将采取的所有措施都可以用于增加对肝炎患者的诊断和治疗。
