Department of Food Science and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas, Brazil.
Department of Food Engineering, Federal University of Paraíba, João Pessoa, Brazil.
Int J Food Sci Nutr. 2021 Sep;72(6):781-793. doi: 10.1080/09637486.2021.1877261. Epub 2021 Jan 24.
This study investigated the effects of consumption of wheat-durum pasta added of inactivated by gamma-irradiation (paraprobiotic) on health and gut microbiota of rats. Twenty-one male rats were divided into three groups as follow: control (Control) receiving standard diet; pasta control (PC) receiving diet containing pasta, and paraprobiotic pasta irradiated (PPBI), receiving paraprobiotic pasta. The serum levels of glucose and total cholesterol were reduced ( < 0.05) in PPBI when compared to the Control ( < 0.05). PPBI showed high abundance ( ˂ 0.05) of and and a lower abundance of compared to Control and PC. Besides, the PPBI showed high abundance ( ˂ 0.05) of , ; , , and in comparison to Control. Specific genera such as and a were more related to PPBI. Findings reveal wheat-durum pasta as a potential vehicle for delivering paraprobiotics .
本研究调查了摄入经伽马射线（部分）灭活的小麦-杜伦 pasta（拟益生菌）对大鼠健康和肠道微生物群的影响。21 只雄性大鼠分为三组：对照组（Control）给予标准饮食；接受含 pasta 的对照组（PC）；接受拟益生菌 pasta 组（PPBI）。与对照组相比，PPBI 的血清葡萄糖和总胆固醇水平降低（ < 0.05）。与 Control 和 PC 相比，PPBI 中 （ < 0.05）的 和 丰度较高，而 的丰度较低。此外，与 Control 相比，PPBI 中 （ < 0.05）的 、 、 、 和 丰度较高。特定属，如 和 ，与 PPBI 更为相关。研究结果表明，小麦-杜伦 pasta 可能是输送拟益生菌的载体。
