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添加灭活的小麦-杜伦小麦面食可降低健康大鼠的血糖和总胆固醇水平,并调节肠道微生物群。

Wheat-durum pasta added of inactivated decreases glucose and total cholesterol levels and modulates gut microbiota in healthy rats.

机构信息

Department of Food Science and Nutrition, Faculty of Food Engineering, University of Campinas, Campinas, Brazil.

Department of Food Engineering, Federal University of Paraíba, João Pessoa, Brazil.

出版信息

Int J Food Sci Nutr. 2021 Sep;72(6):781-793. doi: 10.1080/09637486.2021.1877261. Epub 2021 Jan 24.

Abstract

This study investigated the effects of consumption of wheat-durum pasta added of inactivated by gamma-irradiation (paraprobiotic) on health and gut microbiota of rats. Twenty-one male rats were divided into three groups as follow: control (Control) receiving standard diet; pasta control (PC) receiving diet containing pasta, and paraprobiotic pasta irradiated (PPBI), receiving paraprobiotic pasta. The serum levels of glucose and total cholesterol were reduced ( < 0.05) in PPBI when compared to the Control ( < 0.05). PPBI showed high abundance ( ˂ 0.05) of and and a lower abundance of compared to Control and PC. Besides, the PPBI showed high abundance ( ˂ 0.05) of , ; , , and in comparison to Control. Specific genera such as and a were more related to PPBI. Findings reveal wheat-durum pasta as a potential vehicle for delivering paraprobiotics .

摘要

本研究调查了摄入经伽马射线(部分)灭活的小麦-杜伦 pasta(拟益生菌)对大鼠健康和肠道微生物群的影响。21 只雄性大鼠分为三组:对照组(Control)给予标准饮食;接受含 pasta 的对照组(PC);接受拟益生菌 pasta 组(PPBI)。与对照组相比,PPBI 的血清葡萄糖和总胆固醇水平降低( < 0.05)。与 Control 和 PC 相比,PPBI 中 ( < 0.05)的 和 丰度较高,而 的丰度较低。此外,与 Control 相比,PPBI 中 ( < 0.05)的 、 、 、 和 丰度较高。特定属,如 和 ,与 PPBI 更为相关。研究结果表明,小麦-杜伦 pasta 可能是输送拟益生菌的载体。

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